Reference: Tessier A-J, Cortese M, Yuan C, et al. Consumption of olive oil and dietary quality and risk of dementia-related death. JAMA Network Open. 2024;7(5):e2410021. doi:10.1001/jamanetworkopen.2024.10021.
A recently published analysis of two large, long-term studies found that consuming half a tablespoon or more of olive oil per day lowered the risk of dying of dementia by up to 34% in both women and men. The protective effect of olive oil consumption was even greater in women.
More than 92,000 participants from the Nurses’ Health Study (NHS) and the Health Professionals Follow-Up Study (HPFS) were included in this analysis. The NHS started in 1976 and enrolled 121,700 female registered nurses (ages 30–55). The HPFS began in 1986 as a similar study in men, enrolling 51,525 male healthcare professionals (ages 40–75).
Study participants responded every other year to detailed food frequency questionnaires (FFQ) about their consumption of specific foods. Questions about olive oil were added in 1990. Total olive oil intake was determined by three responses: olive oil used for salad dressings, olive oil added to food or bread, and olive oil used for baking or frying at home.
Olive oil intake frequency was categorized as follows:
• Never, or less than once per month • Less than 4.5 grams (about one teaspoon) per day • Between 4.5 and 7 grams per day • More than 7 grams (about half a tablespoon) per day
About two-thirds of the study participants (65.6%) were women, about a third (34.4%) were men, and the average age at the start of the study was 56 years. Each participant’s FFQs from 1990 to 2014 (or for as long as the participant remained in the study) were totaled and averaged. Average olive oil intake was 1.3 grams per day in both studies.
Participants in the highest olive oil intake group—half a tablespoon or more of olive oil per day— reduced their risk of dying of dementia by 28% to 34%, compared to study participants who never or very rarely consumed olive oil. These results were regardless of other dietary habits and factored in socio-demographic and lifestyle differences.
Deaths due to dementia were confirmed by physician’s review of medical records, autopsy reports, or death certificates of study participants.
It has been proposed that consuming olive oil may lower the risk of dementia-related death by improving blood vessel health, yet the results of this analysis were not impacted by hypertension or high cholesterol in participants.
Limitations of this analysis include its predominantly non-Hispanic white population of healthcare professionals, which reduces the ability to generalize these results across more diverse populations. Also, the FFQs did not dis-tinguish among types of olive oil, which differ in their amounts of polyphenols and other bioactive compounds.
Horiatiki Salad Recipe and The MIND Diet for Brain Health: More Benefits of Olive Oil
I’m a huge fan of both Greek and Middle Eastern salads, the ingredients of which are not only delicious but also mainstays of the MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay) diet, a way of eating designed for brain health. It’s an offshoot of the super-healthy Mediterranean diet and the DASH (Dietary Approaches to Stop Hypertension) diet. Why the distinction? Because the latest research on the MIND diet shows it can slow aging as well as reduce dementia risk. Add this to the list of the benefits of olive oil—it’s one of the super foods that MIND suggests including every day.
Chicken Involtini Recipe, Spotlight on Chicken, A Better Approach to Losing Weight, and Why Workout Plans Go Awry
Want to elevate your next chicken dinner? Chicken involtini, or little bundles, is the delicious answer. Stuffed with spinach and cheese, it ticks all the boxes for flavor. This issue of the newsletter also serves up two studies—one on better ways to get help for losing weight and the other on how to rethink exercise for a better chance at sticking with a plan.
Chicken Involtini
Healthy Ingredient Spotlight
Chicken Breasts
Looking for a lean protein source? A 3-ounce serving of cooked skinless chicken breast delivers between 26 and 30 grams of protein for about 140 calories. You’ll also get B vitamins, particularly niacin and B6, and selenium, an essential trace mineral critical for supporting metabolism, among other functions.
Quick Kitchen Nugget
Pounding Chicken
Pounded cutlets cook quickly and evenly because they have a uniform thickness. What’s more, pounding provides a bigger surface for stuffing which also makes rolling them up easier. It’s important to use a surface that can be easily and thoroughly cleaned, even though you’ll be pounding the chicken between sheets of parchment paper.
A meat mallet is a great tool; the flat side can be used on chicken and pork cutlets, and the side with the little spikes helps tenderize tougher cuts of beef. However, you can also make do with a heavy pan or even a rolling pin. Make sure to rotate the cutlet so you apply the force uniformly and not just to one or two spots. Start with moderate force and increase only if necessary to get an even thickness.
For Your Best Health
A Better Approach to Losing Weight
For a long time, endocrinologist Leigh Perreault, MD, felt uneasy about how weight management was handled in routine medical care. Too often, patients were sent home with vague advice to eat better and exercise more, even when that clearly was not enough.
“There was a moment I put my face in my hands and thought, ‘What am I doing?’ I would write a lot of prescriptions for patients’ diabetes, their blood pressure, their lipids, and all these other conditions,” said Dr. Perreault, a professor of endocrinology, metabolism, and diabetes at the University of Colorado Anschutz School of Medicine who practices in Westminster, Colorado, alongside primary care physicians. But she realized that many of those medications addressed symptoms rather than the root problem. “None of these people want to be on these medications, and I thought if I could just help them with their weight, many of these health concerns would probably go away,” she said. That realization set the stage for a new approach that could soon reshape how weight care would be addressed in primary care.
Dr.Perreault and her colleagues created PATHWEIGH, a structured process that helps people and their primary care teams focus directly on weight management. The program introduces dedicated clinic visits where providers can concentrate specifically on weight-related care instead of squeezing it into a standard appointment.
With funding from the National Institutes of Health, PATHWEIGH was rolled out across UCHealth’s 56 primary care clinics throughout Colorado to evaluate its impact. The pilot included 274,182 patients, making it one of the largest randomized trials ever conducted in this area. Results published in Nature Medicine showed that the program reduced population weight gain by 0.58 kg (about one and a quarter pounds) over 18 months and shifted the overall trend from steady gain to weight loss. Experts estimate that rising obesity rates are driven by an average population weight gain of about 0.50 kg or roughly a half pound every year. Stopping that increase and turning it into even modest weight loss could make a meaningful difference in slowing the obesity epidemic. “While it’s not a significant difference on an individual patient level, it’s a huge deal on a population and public health level,” Dr. Perreault said.
The program also made patients more likely to get help for weight issues. Participation increased the chances of receiving weight-related care by 23%. Most of that care involved lifestyle counseling, but prescriptions for anti-obesity medications doubled during the intervention. Unlike many one-size-fits-all weight-loss programs, PATHWEIGH allows treatment to be customized to each patient. It also reduces the discomfort that often surrounds conversations about weight in medical settings.
“With PATHWEIGH, we showed that we absolutely eliminated population weight gain across all of our primary care, which had never been done previously,” Dr. Perreault said. “If you think about weight loss medicine or surgery or a weight loss program, those are all vehicles to weight loss. We built a highway that we could put all the vehicles on, so there’s actually a process for people to receive weight-related care if they want it.
Dr. Perreault said the program’s success has opened the door to wider adoption. Plans are underway to expand PATHWEIGH beyond Colorado. The Obesity Association, which is developing its first standards of care for obesity, is highlighting the program as a recommended care process. Five health systems across seven states are also considering PATHWEIGH as its creators work toward licensing the model.
Fitness Flash
Why Workout Plans Go Awry
You know you should exercise, so you make a solid plan to do it, but then, in the decisive moment, you opt out. And then you choose to forgo your planned daily exercise again and again. Why? It could be related to what scientists call all-or-nothing thinking.
“Most people are tired and overwhelmed, so in the moment of decision, the immediate costs of exercising feel much bigger than the benefits, making it a low-value choice,” said University of Michigan behavioral scientist Michelle Segar, PhD. “This makes doing ‘nothing’ a prudent choice and desirable exit strategy. Decisions to not exercise are often made outside of awareness—so people are likely unaware that choosing to forgo their exercise plans could be related to having an all-or-nothing mindset.”
She suggests that all-or-nothing thinking is caused by a deeply embedded mindset that leads many people to abandon their exercise plans. “Exercise-related all-or-nothing thinking occurs when a specific exercise plan becomes unworkable,” Dr. Segar explained. “At this moment, when people cannot perfectly adhere to their plan—the ‘all’—they choose not to exercise at all rather than modify the plan.”
While all-or-nothing thinking has been studied in relation to eating and weight, this is the first in-depth research to investigate this phenomenon with exercise, Dr. Segar said. She and her colleagues Jen Taber, John Updegraff, and Alexis McGhee-Dinvaut, all of Kent State University, conducted four focus groups among 27 adults—ages 19 to 79—who tried to exercise but couldn’t stick with it. The study, published in BMC Public Health, uncovered four components that collectively make up an all-or-nothing mindset:
Having rigid, idealized criteria for exercising. For most participants, their “all” constituted rigid standards that had to be met to exercise “right.” They typically say to themselves, “If I do something for under 15 minutes, I feel like I didn’t even exercise. Even if it were dead-out sprints, it just doesn’t factor into my head like I did anything.”
Seeking excuses for not exercising. This component reflects participants actively trying to avoid their intended exercise. They said that exercising the right way took a lot of effort, saying, “It’s hard,” “It hurts,” and “It doesn’t feel good to do.”
Believing exercise was expendable compared to their daily priorities. Participants said things like “When your routine ends up getting crowded with the things that have to be done or should be done, [exercising] is an easy thing to push to the side.”
Being baffled about why they could not stick with exercise. Participants were unable to reconcile their current inactivity even though they could recall having had previous positive experiences exercising, saying things such as “I don’t understand why I don’t exercise. … I’m an educated woman… why can’t I even make a dent in it?”
“The all-or-nothing mindset creates high costs for exercising,” said Dr. Segar. Here’s her advice to overcome it:
Don’t be a prisoner to your exercise past. Know that negative exercise experiences in your past can demotivate you now. Acknowledge that fact and then move forward in more positive and realistic ways.
Don’t blame yourself for not sticking with exercise. Our culture has taught us an exercise formula that sets up most people to fail.
Choose “good enough” over “perfect.” Nothing has to be perfect, including exercise.
These stuffed boneless chicken breasts are browned on the stovetop and then baked in the oven in an olive oil, lemon, and butter sauce. Enjoy on its own or over pasta.
Ingredients
7 tablespoons extra virgin olive oil, divided use
4 garlic cloves, finely chopped
12 ounces fresh baby spinach
1 teaspoon salt, divided use
1 teaspoon freshly ground black pepper, divided use
1/4 teaspoon crushed red pepper flakes
4 skinless boneless chicken breasts, about 2 pounds in total
8-ounce block Emmenthaler or provolone cheese, sliced into 8 sticks
1/3 cup whole wheat flour
1-1/2 cups homemade or store-bought low-sodium chicken stock
Juice of half a lemon
2 tablespoons butter, cut into pieces
1/4 cup fresh flat-leaf parsley, finely chopped
Directions
Step 1
Heat a large oven-safe skillet over medium-high heat. When hot, add 3 tablespoons olive oil and the garlic. Cook the garlic until it becomes translucent, then add the spinach in bunches. As each bunch wilts, add the next. When completely wilted and tender, transfer to a colander and set the skillet aside. Let the spinach cool for 5 minutes, then squeeze with your hands to remove any excess liquid. Transfer to a large glass bowl and toss with 1/2 teaspoon salt, 1/2 teaspoon black pepper, and the red pepper flakes.
Step 2
Slice each breast horizontally to make eight cutlets. One at a time, place each cutlet between two sheets of parchment paper set on a cutting board, and use a kitchen mallet to pound it to about 1/4” thickness. Season each cutlet with the remaining salt and pepper.
Step 3
Top each cutlet with a layer of spinach, then place a stick of cheese in the center. Starting at the narrow end, roll up each cutlet and secure with a wooden skewer or toothpicks to keep the roll closed.
Step 4
Preheat your oven to 375°F. Put the flour in a pie plate and place it next to your stovetop. Wipe out the skillet and reheat it. When hot, add 4 tablespoons olive oil. Roll each bundle in the flour, shake off any excess, and add to the pan, seam side down. Brown on all sides, turning with heat-safe tongs. Deglaze the skillet with the stock, then add the lemon juice and butter. Place the skillet in the oven for 20 minutes or until an instant read thermometer placed in the chicken shows 160°F.
Step 5
Very carefully take the pan out of the oven. If you’d like a thicker sauce, plate the chicken and return the skillet to the stovetop. Bring to a boil and cook down for about 5 minutes. To serve, remove the skewers or toothpicks, drizzle on some sauce, and sprinkle on the parsley.
Baked Ziti Recipe, Spotlight on Whole Wheat Pasta, Understanding al Dente, How the Nose Fends Off Colds and Fighting Age-Related Muscle Loss
When it comes to comfort food, few dishes can top baked ziti, with its luscious sauce and melted cheeses. And it doesn’t take much effort for all that reward! I’m sharing interesting research that may explain why some people are more prone to colds than others as well as a reminder about maintaining muscle as we age.
Baked Ziti
Healthy Ingredient Spotlight
Whole Wheat Pasta
To add more nutrients and fiber to your ziti, opt for whole wheat pasta. It’s made from the entire wheat kernel—bran, germ, and endosperm—and retains its vitamins and minerals. While it takes a bit longer to cook, follow package directions to be sure it’s al dente.
Quick Kitchen Nugget
Understanding al Dente
Al dente literally means to the tooth—firm when bitten yet not hard or raw tasting. Most Italian cooks boil pasta to this stage regardless of the recipe. Americans tend to like their pasta more tender. But when it will be twice cooked, as with ziti, lasagna, and stuffed shells, it needs to be al dente before it goes into the oven or else it will be too soft.
If your pasta box doesn’t list al dente cooking time, test a piece about 2 minutes sooner than the general directions and see whether it has a bit of bite. If it’s too firm, check it again in a minute.
For Your Best Health
How the Nose Fends Off Colds
When rhinovirus, the most common cause of the common cold, enters the nasal passages, the cells lining the nose immediately begin working together to fight the infection. These cells activate a wide range of antiviral defenses designed to limit the virus and stop it from spreading. In a study published in the journal Cell Press Blue, researchers show that this early response plays a key role in whether a person becomes sick and how severe their symptoms become. The findings suggest that the body’s reaction to rhinovirus often matters more than the virus itself.
“As the number one cause of common colds and a major cause of breathing problems in people with asthma and other chronic lung conditions, rhinoviruses are very important in human health,” said senior author Ellen Foxman, MD, PhD, of the Yale School of Medicine. “This research allowed us to peer into the human nasal lining and see what is happening during rhinovirus infections at both the cellular and molecular levels.”
To closely observe how nasal cells respond to infection, the research team built a lab-grown model of human nasal tissue with multiple cell types found in the human airway, including mucus-producing cells and cells with cilia, the tiny hairlike structures that help move mucus and trapped particles out of the lungs. “This model reflects the responses of the human body much more accurately than the conventional cell lines used for virology research,” Dr. Foxman said.
Using this model, the researchers were able to monitor how thousands of individual cells respond together during infection. They also examined what happened when the cellular sensors responsible for detecting rhinovirus were blocked. These experiments revealed a powerful defense system coordinated by interferons, which are proteins that interfere with viral entry and replication.
When nasal cells detect rhinovirus, they release interferons that activate antiviral defenses not only in infected cells but also in nearby healthy cells. This coordinated response makes it difficult for the virus to reproduce and spread. If interferon activity begins quickly, the infection can be contained early. When the researchers blocked this response, the virus spread rapidly, infecting many more cells and causing significant damage. In some cases, the infected organoids did not survive.
“Our experiments show how critical and effective a rapid interferon response is in controlling rhinovirus infection, even without any cells of the immune system present,” said first author Bao Wang, PhD, of the Yale School of Medicine.
The study also uncovered additional responses that occur when viral replication increases. Under these conditions, rhinovirus can activate a separate sensing system that leads both infected and uninfected cells to produce large amounts of mucus and inflammatory signals. This reaction can contribute to airway inflammation and breathing difficulties in the lungs. According to the researchers, these pathways may offer useful targets for treatments aimed at reducing harmful symptoms while supporting effective antiviral defenses.
“Our study advances the paradigm that the body’s responses to a virus, rather than the properties inherent to the virus itself, are hugely important in determining whether or not a virus will cause illness and how severe the illness will be,” Dr. Foxman said. “Targeting defense mechanisms is an exciting avenue for novel therapeutics.”
Fitness Flash
Fighting Age-Related Muscle Loss
A new study in mice is giving scientists fresh clues about why our muscles lose strength as we get older and why exercise remains one of the most reliable ways to fight it.Researchers at Duke-NUS Medical School found that a gene regulator called DEAF1 seems to push a key muscle-maintenance system into overdrive as we age. When we’re young, the system known as mTORC1 helps build and repair muscle. But later in life, it can get stuck in high gear and begin to damage muscle cells instead.
“The mTORC1 pathway is essential for muscle growth yet becomes chronically overactive in aging—a paradox that has made it challenging to pinpoint what drives this dysregulation,” said the study’s senior author Hong-Wen Tang, PhD, an assistant professor in the Cancer and Stem Cell Program at Duke-NUS and Singapore General Hospital.
Until now, scientists didn’t know what caused this shift. “Identifying DEAF1 fills an important gap in understanding how age-related stress signals become hardwired into a persistent anabolic state that ultimately harms muscle cells,” Dr. Tang said.
The study suggests DEAF1 essentially hits the gas on a system already running too fast. By pushing mTORC1 into overdrive, DEAF1 causes muscles to make too many proteins, fail to clear damaged ones, and gradually weaken.
One of the most surprising findings: Exercise reverses this process by lowering DEAF1 levels. That means in addition to building muscle, physical activity helps reset the core cellular pathways that keep muscles healthy. “It was a striking discovery,” said Dr. Tang. “It shows that exercise doesn’t just fix damage; it targets the switch that causes muscle aging in the first place.”
Scientists didn’t just look at whether exercise keeps muscles strong—they wanted to know how it does it. They put aging mice through endurance workouts, including an exhausting treadmill run. For comparison, another group of older mice stayed sedentary. After the workouts, the exercising mice showed big drops in mTORC1, the overactive pathway linked to muscle loss and function known as sarcopenia.
Researchers found that exercise lowers DEAF1 through a well-known set of longevity genes called FOXO. When activated during exercise, FOXO suppresses DEAF1—lifting the foot off the gas pedal—and helps mTORC1 return to normal. Their work highlights a new biological pathway—the FOXO-DEAF1-mTORC1 axis—that helps explain why muscles weaken with age and why exercise remains such a powerful antidote to age-related decline.
This delectable dish starts with a rich yet quick tomato sauce. You can substitute a 15-ounce can of diced tomatoes with their juice for the fresh tomatoes but add it after the tomato paste.
Ingredients
3 tablespoons extra virgin olive oil, plus more for the baking dish and drizzling
2 garlic cloves, chopped
1 pound tomatoes, any type, coarsely chopped
One 6-ounce can tomato paste
1 teaspoon sugar
1 teaspoon fine sea salt
1/2 teaspoon crushed red pepper flakes, plus more to taste
1/2 teaspoon freshly ground black pepper
1 pound ziti
16 ounces ricotta cheese
12 ounces mozzarella, thinly sliced
1/3 cup freshly grated Parmigiano-Reggiano cheese
Directions
Step 1
Brush a 13-inch by 9-inch baking dish with olive oil; set aside.
Step 2
Heat a medium saucepan over medium heat. When hot, add the 3 tablespoons olive oil and garlic and sauté for 3 minutes, then add the tomatoes. Cook, stirring constantly, until the tomatoes become soft, then push them to the outsides of the pan. Add the tomato paste and cook it until it becomes fragrant and darkens in color, about 5 minutes. Mix the paste with the tomatoes and garlic, then press with a masher to release all of the tomatoes’ juices. Stir in the sugar, salt, and both peppers and continue cooking for 10 minutes.
Step 3
Meanwhile, preheat your oven to 350°F. Cook the ziti according to the package directions until al dente, then drain.
Step 4
Off the heat, stir the ricotta into the sauce, then fold in the pasta. Transfer the mixture to the baking dish. Top with overlapping slices of mozzarella, then sprinkle on the grated cheese.
Step 5
Bake for 25 minutes, until the cheeses are bubbly. Cool for 10 minutes before serving.
Tricolore Soup Recipe, Spotlight on Kidney Beans, Colanders and Strainers, Benefits of Monk Fruit, and Workouts Burn More Calories than Previously Thought
I love a hearty soup that delivers nourishing warmth with great taste. My combination of beans, barley, and broccoli is a flavorful hit! If you’re a fan of monk fruit as a sweetener, you’ll be wowed by the nutritional bounty of this gourd. I’m also sharing the latest research on calories burned during exercise—motivation to get moving.
Tricolore Soup
Healthy Ingredient Spotlight
Red Kidney Beans
Named for their red color and their shape, kidney beans are a type of legume that come in light- and dark-red shades. Because they’re very firm, they retain their texture well in recipes. Kidney beans are a great source of fiber and protein, delivering 7 grams of each in a half-cup. You’ll also get folate and vitamin B1 along with minerals including iron, manganese, and phosphorus. What’s more, eating beans helps control cholesterol and blood sugar and may boost heart and colon health.
Quick Kitchen Nugget
Colanders and Strainers
Though many recipes call for straining or draining foods, they rarely specify what tool to use. Depending on the specific task at hand, you’ll need either a colander or a strainer. What’s the difference? The overall size and the size of the openings. Simply put, a colander is a footed bowl with two handles and large holes for draining foods like just-boiled potatoes and pasta and rinsing raw fruits, vegetables, and even canned beans. A strainer is a handheld gadget with a scoop-like surface made of mesh for jobs like straining cocoa to remove lumps or sifting confectioners’ sugar over baked goods. It’s also handy when you want to strain out very small ingredients, like seeds. Some strainers have a finer mesh than others. In general, it’s very helpful to have at least two sizes of each tool, typically made from stainless steel for durability.
For Your Best Health
Benefits of Monk Fruit
Scientists are taking a closer look at monk fruit and discovering it’s more than just a zero-calorie natural sweetener. Luo han guo (Siraitia grosvenorii), more commonly known as monk fruit, is a long-living vine that belongs to the gourd family, the same plant group as cucumbers and squash. It’s native to southern China, where it has been used for centuries in traditional foods and remedies. In recent years, monk fruit has drawn scientific attention because it contains high levels of antioxidants, which help protect cells from damage caused by unstable molecules—free radicals which have been linked to aging and many chronic diseases. New findings published in the Journal of the Science of Food and Agriculture looked at the specific chemical compounds of monk fruit and how they may support health.
One of the most important features of monk fruit is its abundance of what’s called secondary metabolites. These are natural plant chemicals that are not required for basic human growth but often play a role in health. In this case, researchers concentrated on three major groups: terpenoids, flavonoids, and amino acids. They examined both the peel and the pulp of four different monk fruit varieties and were able to identify where these compounds are concentrated and how they behave biologically. The study further explored how they interact with antioxidant receptors and other biological targets. (Receptors are structures in cells that receive chemical signals and trigger responses in the body.) These interactions influence various biological pathways, which are step-by-step processes that help regulate functions such as inflammation, metabolism, and cellular protection. Understanding these pathways helps explain why monk fruit may have health promoting properties beyond its use as a natural sweetener.
The researchers emphasized that not all monk fruit is chemically identical. Different varieties can contain different levels and combinations of active compounds. As the authors explained, “[I]t is crucial to conduct an in-depth investigation on the high-resolution metabolic profiles of different luo han guo varieties, providing valuable insights into the nutritional and health characteristics as well as the manufacturing suitability of the various resources available from this plant.” This type of detailed chemical mapping helps scientists determine which varieties may be best suited for food products, supplements, or other uses.
Fitness Flash
Workouts Burn More Calories than Previously Thought
For years, researchers have debated whether the body treats energy like a fixed paycheck or a flexible bonus system. One idea suggests that when people move more, the body shifts energy away from other tasks to pay for that activity. The other model proposes that energy use can expand, allowing total daily expenditure to rise as activity increases. Researchers, led by scientists at Virginia Tech working with colleagues from the University of Aberdeen and Shenzhen University, set out to learn which of these ideas best reflect what actually happens across different activity levels.
To do so, the team measured total energy expenditure, meaning the total number of calories burned in a day, among 75 participants between the ages of 19 and 63, with widely varying activity levels that ranged from largely inactive to ultra-endurance running. “Our study found that more physical activity is associated with higher calorie burn, regardless of body composition, and that this increase is not balanced out by the body reducing energy spent elsewhere,” said Kevin Davy, PhD, a professor in the Department of Human Nutrition, Foods, and Exercise at Virginia Tech and the principal investigator of the study. Physical activity continues to affect the body even after the movement itself has ended. More movement leads to more calories burned.
To measure calories burned, the researchers had the participants drink special forms of oxygen and hydrogen and provide urine samples over a two-week period. Oxygen leaves the body as both water and carbon dioxide, while hydrogen exits only as water. By comparing how much of each isotope was lost, researchers could estimate how much carbon dioxide participants produced and, in turn, how much energy they used. Physical activity was tracked using a small waist-worn sensor that recorded movement in multiple directions.
The results showed that as people moved more, their total energy use increased accordingly. The body did not appear to compensate by dialing down energy use elsewhere. Essential functions such as breathing, blood circulation, and temperature regulation continued to require the same amount of energy, even as physical activity rose. This means the body does not clearly offset or cancel out the extra calories burned through movement.
The researchers also observed a strong connection between higher activity levels and reduced time spent sitting. Simply put, people who move more tend to spend less time being inactive overall.
“Tricolore” refers to the three colors of the Italian flag, but this recipe has surprising choices for the red, white, and green—kidney beans, barley, and broccoli! Notes: Choose hull-less rather than pearl barley for better taste and more fiber. Always save and freeze Parmigiano-Reggiano rinds as they add great flavor to soups and stews.
Ingredients
1 cup hull-less barley, uncooked
3 tablespoons extra virgin olive oil, plus more for drizzling
2 garlic cloves, minced
1 pound broccoli florets, coarsely chopped
6 cups homemade or store-bought low-sodium chicken or vegetable broth
Optional: rind from a block of Parmigiano-Reggiano cheese
One 15.5-ounce can red kidney beans, rinsed and drained
Fine sea salt to taste
Freshly ground black pepper to taste
Shavings of Parmigiano-Reggiano cheese
Directions
Step 1
In a medium saucepan, bring the barley and 4 cups of water to a boil. Lower the heat to a simmer and cook until tender, an hour or more. When the barley is done, all the water should have evaporated. Check it regularly in case the water evaporates before the barley is cooked through.
Step 2
Heat a stockpot over medium-high heat. When hot, add the 3 tablespoons olive oil and the garlic. Sauté until the garlic softens. Add the broccoli, broth, and, if using, the cheese rind. Bring to a simmer and cook until the broccoli is tender, about 12 minutes. Add in the cooked barley and beans and heat through. Season to taste with salt and pepper.
Step 3
Serve with large shavings of cheese and a drizzle of olive oil.
Pistachio Layer Cake Recipe, Spotlight on Buttermilk, How to Sift Dry Ingredients, Volunteering to Keep your Brain Younger, plus Tea, Coffee, and Women’s Bone Health
This romantic pistachio and white chocolate layer cake is delicious any time of the year, but it’s especially fitting for Valentine’s Day. This is also an excellent time to think about helping others, and a new study of volunteering made a link between selfless acts of service and helping brain health. I’m also sharing research on the effects of tea and coffee on women’s bone health—the results will surprise you.
Pistachio Layer Cake
Healthy Ingredient Spotlight
Buttermilk
True buttermilk is the fermented liquid that separates from the fat mass when churning butter. The buttermilk sold in supermarkets is milk that has fermented thanks to the addition of live cultures. Though rich and creamy, buttermilk is low in fat with a high acidity level. It makes baked goods very fluffy—that’s why buttermilk biscuits and buttermilk pancakes are so popular. In a pinch, you can create a cup of buttermilk by adding 1 tablespoon of lemon juice or distilled vinegar to 1 cup of milk and letting it sit for a few minutes until it curdles.
Quick Kitchen Nugget
Sifting Dry Ingredients
Whether with a dedicated sifter or a fine mesh strainer with a spoon acting as a pusher, sifting dry ingredients is a great way to better mix them as well as get rid of any possible lumps, especially with cocoa powder and confectioners’ sugar. Some pre-ground nut flours, like almond meal, can also develop clumps, but you may need a tool with a wider mesh to sift them. Keep in mind that when sifting numerous ingredients together, you’ll still need to whisk them to fully distribute them.
For Your Best Health
Volunteering to Keep your Brain Younger
Strong social ties are often linked to better health, and new research adds a brain benefit to that list. Researchers from The University of Texas at Austin and the University of Massachusetts Boston report that regularly helping people outside your household can noticeably slow cognitive decline in middle-aged and older adults, even if it’s just a few hours a week.
The researchers followed more than 30,000 adults in the US for two decades and found the decline was reduced by about 15% to 20% among those who either volunteered formally or helped in informal ways, such as supporting neighbors, family, or friends. Both formal volunteering and informal acts were linked to noticeably slower cognitive decline over time. The benefits added up year after year and didn’t require a huge time commitment. Even modest everyday helping packed a powerful mental payoff.
“Everyday acts of support—whether organized or personal—can have lasting cognitive impact,” said Sae Hwang Han, PhD, Assistant Professor of Human Development and Family Sciences at UT who led the study. “What stood out to me was that the cognitive benefits of helping others weren’t just short-term boosts but cumulative over time with sustained engagement, and these benefits were evident for both formal volunteering and informal helping. And in addition to that, moderate engagement of just two to four hours was consistently linked to robust benefits.”
These results strengthen the case for thinking about volunteering, helping, and neighborhood connection as public health issues. This may be especially important later in life, when conditions tied to cognitive decline and impairment, including Alzheimer’s, are more likely to develop.
Related work led by Dr. Han found that volunteering helped counter the harmful effects of chronic stress on systemic inflammation, a known biological pathway linked to cognitive decline and dementia. The benefit was strongest among people with higher levels of inflammation. Taken together, these findings suggest helping others may support brain health in more than one way. It may reduce the physical strain linked to stress, and it may strengthen social bonds that provide psychological, emotional, and cognitive support. As societies age and concerns about loneliness and isolation grow, the results also support continued efforts to keep people involved in ways that let them contribute, even after cognitive decline has begun.
“Many older adults in suboptimal health often continue to make valuable contributions to those around them,” Dr. Han said, “and they also may be the ones to especially benefit from being provided with opportunities to help.”
Fitness Flash
Tea, Coffee, and Women’s Bone Health
An investigation from Flinders University in South Australia sheds new light on how two widely consumed drinks, coffee and tea, could play a role in bone health for women later in life. The study, published in the journal Nutrients, monitored nearly 10,000 women aged 65 and older for 10 years to examine whether regularly drinking coffee or tea was connected to changes in bone mineral density (BMD).
BMD is a central marker used to assess osteoporosis risk. Osteoporosis affects one in three women over 50 and leads to millions of fractures every year, making bone health an important global issue. Because coffee and tea are part of daily routines for billions of people, researchers noted that understanding their long-term effects on bones is essential. Previous findings have often been inconsistent, and few studies have followed such a large group across an entire decade.
The researchers used information from the Study of Osteoporotic Fractures, drawing on repeated measures of beverage intake and BMD at the hip and femoral neck. These areas are closely tied to fracture risk. Throughout the 10-year period, participants regularly reported how much coffee and tea they consumed. At the same time, bone density was assessed using advanced imaging tools.
Results showed that women who drank tea had slightly higher total hip BMD than those who did not. Although the improvement was small, it was statistically significant and may matter when considering the health of a large population.
“Even small improvements in bone density can translate into fewer fractures across large groups,” said Adjunct Associate Professor Enwu Liu, PhD, from the College of Medicine and Public Health.
Findings for coffee were more varied. Moderate intake, roughly two to three cups a day, was not associated with harm. However, consuming more than five cups per day was linked to lower BMD, indicating that very high levels of coffee could negatively affect bone strength. Women with higher lifetime alcohol intake appeared particularly vulnerable to coffee’s negative effects, whereas tea showed stronger benefits in women with obesity.
Ryan Liu, co-author of the study, explains that tea is rich in catechins, compounds that may encourage bone formation and help slow bone loss. “Coffee’s caffeine content, by contrast, has been shown in laboratory studies to interfere with calcium absorption and bone metabolism, though these effects are small and can be offset by adding milk,” he said.
Dr. Enwu Liu noted that the research suggests drinking tea daily may be an easy way to support bone health as people grow older. “While moderate coffee drinking appears safe, very high consumption may not be ideal, especially for women who drink alcohol,” he said.
The researchers emphasized that while the results are statistically meaningful, the differences are not dramatic enough to require sweeping lifestyle changes. “Our results don’t mean you need to give up coffee or start drinking tea by the gallon,” said Dr. Liu. “But they do suggest that moderate tea consumption could be one simple way to support bone health and that very high coffee intake might not be ideal, especially for women who drink alcohol. While calcium and vitamin D remain cornerstones of bone health, what’s in your cup could play a role too. For older women, enjoying a daily cup of tea may be more than a comforting ritual; it could be a small step toward stronger bones.”
Pistachio-based cake layers are filled and iced with a whipped white chocolate ganache. The thin layer of raspberry preserves is a great counterpoint to the sweetness of the chocolate. Use a coffee bean or nut grinder to turn raw (unroasted and unsalted) pistachios into a ground powder. Note: If you don’t have buttermilk on hand, see the Healthy Ingredient Spotlightin our weekly newsletter for alternatives.
Ingredients
For the frosting:
12 ounces white chocolate
1-1/2 cups heavy cream
For the cake layers:
3 cups all-purpose flour
2 teaspoons baking powder
1 teaspoon baking soda
1/2 teaspoon salt
4 ounces unsalted butter, well softened
1/2 cup olive oil
1-1/2 cups granulated sugar
4 large eggs
1 cup buttermilk
1 cup finely ground pistachios from about 4 ounces of raw nuts
2 teaspoons vanilla extract
To assemble:
1/2 cup raspberry preserves
2 ounces pistachios, coarsely chopped
Directions
Step 1
Start by making the frosting. Place the chocolate in a glass bowl. Heat the cream just to a simmer and pour over the chocolate. Let sit for 3 minutes, then whisk until smooth (if the heat of the cream wasn’t enough to melt all the chocolate, you can microwave the bowl for 30 seconds, then stir). Chill in the fridge for 4 hours to firm up.
Step 2
Meanwhile, make the cake layers. Preheat your oven to 350°F. Line two 9-inch cake pans with parchment paper; set aside.
Step 3
In a large bowl, sift together the flour, baking powder, baking soda, and salt; set aside.
Step 4
In the bowl of a stand mixer fitted with the paddle attachment or in a large bowl using a hand mixer, cream the butter, olive oil, and sugar until smooth, about 3 minutes. Add the eggs one at a time, then the buttermilk, ground pistachios, and vanilla. Whisk in the dry ingredients, then use a spatula to be sure all the flour is well incorporated.
Step 5
Divide the batter between the two pans and bake for 30 minutes or until the tip of a sharp knife inserted in the center of each cake comes out clean (rotate the pans halfway through for even baking). Let cool to room temperature.
Step 6
Ater the frosting has chilled, whip it on high speed until it thickens to frosting consistency, about 1 minute. Spread about 1/3 over one of the cake layers. Spread the raspberry preserves on the underside of the other layer, then stack it on top of the bottom layer. Frost the top and sides of the cake with the remaining frosting. Sprinkle the top with the chopped pistachios.
Black Dal Recipe, Spotlight on Black Lentils, How to Store Lentils, Sorbitol and The Liver, and More Muscle, Younger Brain
When it comes to dark leafy greens, kale occupies a heightened position thanks to its wide range of nutrients. And yet, shockingly, researchers have found that the body doesn’t absorb as many of them as hoped…unless you eat it with a healthy fat source, like extra virgin olive oil. I’m also sharing the trick to make this hearty green more tender, which also involves olive oil. It’s another reason why these two ingredients are a match made in heaven.
Black Dal
Healthy Ingredient Spotlight
Black Lentils
Lentils belong to the broader family of legumes, which includes beans and dried peas. But unlike those others, lentils don’t need an overnight soak in water, so there’s less prep needed. Also available in red, green, and yellow, lentils are rich in protein, fiber, and iron, along with dozens of other nutrients. Because of their deep color, round shape, and tiny size, black lentils are often called caviar or beluga lentils. Black dal traditionally uses urad dal, a mung bean that’s not a true lentil, though it is a legume. However, black lentils—which you can find at specialty markets or online—work extremely well for dal and many other recipes.
Quick Kitchen Nugget
How to Store Lentils
Like other legumes, lentils keep best in a cool, dry cabinet, either in their original packaging or a tightly sealed glass container. They’re most flavorful (and take less time to cook) when used within a year of packaging. Before cooking, check them for any debris, like tiny stones, and rinse with cold water, then drain.
For Your Best Health
Sorbitol and The Liver
Sweeteners such as aspartame, found in Equal packets, sucralose (Splenda), and sugar alcohols are widely promoted as healthier options than foods made with refined sugar (glucose). Many people turn to them hoping to reduce health risks linked to sugar and cut calories. But new scientific evidence is now calling that into question. Recent findings suggest that the sugar alcohol sorbitol in particular may not be as harmless as it is often assumed to be.
The findings come from a study published in Science Signaling that builds on years of research from the laboratory of Gary Patti, PhD, at Washington University in St. Louis into how fructose affects the liver and other organs. Dr. Patti, the Michael and Tana Powell Professor of Chemistry in Art & Sciences and a professor of genetics and medicine at WashU Medicine, has previously shown that fructose processed by the liver can be diverted in ways that fuel cancer cell growth. Other studies have linked fructose to steatotic liver disease, a condition that now affects about 30% of adults worldwide.
One of the most unexpected results of the new study is that sorbitol is essentially “one transformation away from fructose,” according to Dr. Patti. Because of this close relationship, sorbitol can trigger effects similar to those caused by fructose itself.
Using zebrafish as a model, Dr. Patti and his team showed that sorbitol, commonly found in low-calorie candies and gums and naturally present in stone fruits, can be produced inside the body. Enzymes in the gut can generate sorbitol, which is then transported to the liver and converted into fructose.
The team also discovered that the liver can receive fructose through multiple metabolic routes. Which pathway dominates depends on how much glucose and sorbitol a person consumes as well as the specific mix of bacteria living in their gut.
Most earlier studies of sorbitol metabolism focused on disease states such as diabetes, where high blood sugar leads to excess sorbitol production. Dr. Patti explained that sorbitol can also be created naturally in the gut after a meal, even in people without diabetes.
The enzyme responsible for making sorbitol does not bind easily to glucose, meaning glucose levels must rise significantly before the process begins. That is why sorbitol production has long been linked to diabetes. However, the zebrafish experiments showed that glucose levels in the intestine can become high enough after you eat to activate this pathway even under normal conditions. “It can be produced in the body at significant levels,” said Dr. Patti. “But if you have the right bacteria, turns out, it doesn’t matter.”
Certain Aeromonas bacterial strains are able to break down sorbitol and convert it into a harmless bacterial by-product. When these bacteria are present and functioning well, sorbitol is less likely to cause problems. “However, if you don’t have the right bacteria, that’s when it becomes problematic. Because in those conditions, sorbitol doesn’t get degraded, and as a result, it is passed on to the liver,” he said.
Once sorbitol reaches the liver, it is converted into a fructose derivative. This raises concerns about whether alternative sweeteners truly offer a safer option than table sugar, especially for people with diabetes and other metabolic disorders who often rely on products labeled as sugar-free.
At low levels, such as those typically found in whole fruits, gut bacteria are usually effective at clearing sorbitol. The trouble begins when the amount of sorbitol exceeds what these microbes can handle. This overload can happen when large amounts of glucose are consumed, leading to an increased production of sorbitol from glucose, or when the diet itself contains high levels of sorbitol. Even individuals with helpful bacteria may run into problems if their intake of glucose and sorbitol becomes too high, since the microbes can be overwhelmed.
Avoiding both sugar and sugar substitutes has become increasingly difficult, as many processed foods contain several forms of sweeteners at once. Dr. Patti said he was surprised to learn that his own favorite protein bar contained a significant amount of sorbitol.
Further research is needed to understand exactly how gut bacteria clear sorbitol. What is becoming clear, however, is that the long-held assumption that sugar alcohols, also known as polyols, are simply eliminated without harm may not be accurate. “We do absolutely see that sorbitol given to animals ends up in tissues all over the body,” he said. The overall message from the research is that replacing sugar is not as simple as it may seem. As Dr. Patti put it, “there is no free lunch” when it comes to sugar alternatives, and many metabolic pathways can ultimately lead back to liver dysfunction.
Fitness Flash
More Muscle, Younger Brain
New research shows that people who have more muscle and a lower visceral fat-to-muscle ratio tend to show signs of a younger biological brain age. This conclusion comes from a study recently presented at the annual meeting of the Radiological Society of North America. Visceral fat refers to the fat stored deep in the abdomen around key internal organs.
“Healthier bodies with more muscle mass and less hidden belly fat are more likely to have healthier, youthful brains,” said senior study author Cyrus Raji, MD, PhD, Associate Professor of Radiology and Neurology in the Department of Radiology at the Mallinckrodt Institute of Radiology at Washington University School of Medicine in St. Louis. “Better brain health, in turn, lowers the risk for future brain diseases, such as Alzheimer’s.”
Brain age is an estimate of how old the brain appears biologically, based on its structure as seen through an MRI. A whole-body MRI can track muscle mass, which serves as a marker for efforts to reduce frailty and strengthen overall health. Estimated brain age from structural scans may also shed light on risk factors for Alzheimer’s disease, including muscle loss.
“While it is commonly known that chronological aging translates to loss of muscle mass and increased hidden belly fat, this work shows that these health measures relate to brain aging itself,” Dr. Raji said. “It shows muscle and fat mass quantified in the body are key reflectors of brain health, as tracked with brain aging.”
The study evaluated 1,164 healthy adults across four research sites using whole-body MRI. Participants had a mean chronological age of 55.17 years. Imaging included T1-weighted MRI sequences, which highlight fat as bright and fluid as dark, providing a clear view of muscle, fat, and brain tissue. An artificial intelligence (AI) algorithm measured total normalized muscle volume, visceral fat (hidden belly fat), subcutaneous fat (fat under the skin), and predicted brain age.
The data indicated that individuals with a higher visceral fat-to-muscle ratio had higher predicted brain age. Subcutaneous fat showed no meaningful association with how old the brain appeared. “The participants with more muscle tended to have younger-looking brains, while those with more hidden belly fat relative to their muscle had older-looking brains,” Dr. Raji said. “The fat just under the skin wasn’t related to brain aging. In short, more muscle and a lower visceral fat-to-muscle ratio were linked to a younger brain.”
Dr. Raji explained that focusing on building muscle and reducing visceral fat are realistic and actionable goals. Whole-body MRI and AI-based brain age estimates can offer clear benchmarks for programs designed to lower visceral fat while maintaining or increasing muscle. He also noted that the results highlight the close connection between physical health and brain health.
“This research has validated widely held hypotheses about the association between body composition biomarkers and brain health and provides a foundation for those biomarkers to be included in future trials of various metabolic interventions and treatments.”
Commonly prescribed glucagon-like peptide-1 (GLP-1) weight loss medications, including Ozempic, are effective at reducing body fat but may also contribute to muscle loss. Dr. Raji suggested that the study’s findings could help guide the development of next-generation therapies. These future treatments may aim to reduce visceral fat more than subcutaneous fat while protecting muscle mass.
“Losing fat—especially visceral fat—while preserving muscle volume would have the best benefit on brain aging and brain health based on insights from our work,” he said. “Thus, our study can inform future treatments by promoting research that quantifies MRI of body fat, muscle, and brain age, which can help determine the optimal dosing regimens for GLP-1s to achieve the best outcomes in body and brain health.”
If you’re new to lentils, this flavorful recipe makes a great introduction. I’ve streamlined the number of spices used in traditional recipes because garam masala already incorporates the essentials—coriander, black pepper, cardamom, cinnamon, cloves, ginger, and nutmeg, among others. This makes a hearty meatless meal, a soup, or a side dish—scoop it up with a piece of your favorite Indian bread.
Ingredients
2 cups black lentils
3 tablespoons extra virgin olive oil, plus more for drizzling
1 small onion, minced
2-inch piece ginger, minced
2 garlic cloves, minced
One 6-ounce can tomato paste
2 teaspoons garam masala
1/2 teaspoon cayenne pepper
1 cinnamon stick
1 cup homemade or store-bought low-sodium chicken or vegetable broth
2 tablespoons unsalted butter
1/2 cup heavy cream
Optional garnish: chopped fresh cilantro
Directions
Step 1
Rinse the lentils, and then put them in a stockpot or Dutch oven. Add enough cold water to cover them by 2 or 3 inches. Bring to a rolling boil and cook for 5 minutes, then lower the heat to a simmer. Cook for about 45 minutes, stirring occasionally, until the lentils are tender but still hold their shape. (If the water level gets too low, add more water as needed to keep them covered). Drain if needed and transfer to a bowl.
Step 2
Rinse the pot and heat over medium-high heat. When it’s hot, add the olive oil and onions; cook until they become translucent, and then add the minced ginger and garlic and cook until fragrant. Push the vegetables to the sides of the pot and add the tomato paste in the center. Cook, stirring constantly, until the paste deepens in color, then mix into the vegetables. Add the garam masala, cayenne pepper, cinnamon stick, broth, and cooked lentils. Simmer for 15 minutes, stirring frequently, to infuse the lentils with the spices. Then stir in the butter and cream and simmer for 2 minutes. Serve with a drizzle of olive oil and a sprinkle of cilantro if desired.
Yields 6 main servings, 6 side servings
For Your Best Health
The MIND Diet for Brain Health: More Benefits of Olive Oil
According to a new study from researchers at the Columbia University Mailman School of Public Health and The Robert Butler Columbia Aging Center, a very specific brain-boosting diet has been linked to reduced dementia risk and a slower pace of aging. The study, “Diet, Pace of Biological Aging, and Risk of Dementia in the Framingham Heart Study,” published in the Annals of Neurology, also explains how the diet helps slow down the processes of biological aging.
“Much attention to nutrition in dementia research focuses on the way specific nutrients affect the brain,” said Daniel Belsky, PhD, associate professor of epidemiology and a senior author of the study. “We tested the hypothesis that healthy diet protects against dementia by slowing down the body’s overall pace of biological aging.”
The researchers used data from the second generation of the Framingham Heart Study, the Offspring Cohort. Participants were 60 years of age or older and free of dementia and had available dietary, epigenetic, and follow-up data. Follow-up was done at nine examinations, approximately every 4 to 7 years, which included a physical exam, lifestyle-related questionnaires, blood sampling, and, starting in 1991, neurocognitive testing. Of 1,644 participants included in the analyses, 140 developed dementia.
To measure the pace of aging, the researchers used an epigenetic clock called DunedinPACE developed by Dr. Belsky and colleagues at Duke University and the University of Otago in Dunedin, New Zealand. The clock measures how fast a person’s body is deteriorating as they grow older, “like a speedometer for the biological processes of aging,” explained Dr. Belsky.
“We have some strong evidence that a healthy diet can protect against dementia,” said Yian Gu, PhD, associate professor of neurological sciences at Columbia University Irving Medical Center and the other senior author of the study, “but the mechanism of this protection is not well understood.” Past research linked both diet and dementia risk to an accelerated pace of biological aging. “Testing the hypothesis that multi-system biological aging is a mechanism of underlying diet-dementia associations was the logical next step,” explained Dr. Belsky.
The research determined that higher adherence to the MIND diet slowed the pace of aging as measured by DunedinPACE and reduced risks for dementia and mortality. Furthermore, slower DunedinPACE accounted for 27% of the diet-dementia association and 57% of the diet-mortality association.
“Our findings suggest that slower pace of aging mediates part of the relationship of healthy diet with reduced dementia risk, and therefore, monitoring pace of aging may inform dementia prevention,” said first author Aline Thomas, PhD, of the Columbia Department of Neurology and Taub Institute for Research on Alzheimer’s Disease and the Aging Brain. “However, a portion of the diet-dementia association remains unexplained, therefore we believe that continued investigation of brain-specific mechanisms in well-designed mediation studies is warranted.”
“We suggest that additional observational studies be conducted to investigate direct associations of nutrients with brain aging, and if our observations are also confirmed in more diverse populations, monitoring biological aging may indeed inform dementia prevention,” noted Dr. Belsky.
Exactly What Is the MIND Diet?
MIND is a hybrid of the Mediterranean and DASH diets, tailored to reflect key findings from nutrition and dementia research. It details serving sizes of specific foods to focus on and which to limit, primarily those high in saturated fat, which is known to negatively affect brain health.
Foods and portions to eat every day: 1/2 to 1 cup green leafy vegetables, 1/2 cup other vegetables, 2 tablespoons extra virgin olive oil, and three 1-ounce servings of whole grains.
Foods and portions to eat over the course of each week: 5 ounces nuts, 2-1/2 cups berries, 1-1/2 cups legumes, two 3-to-5-ounce servings of skinless poultry, and 3-to-5 ounces fish.
Foods to limit to these weekly totals: three or fewer 3-to-5-ounce servings of red and processed meats, 1 ounce whole-fat cheese, 1 fried or fast food, and 4 sweet servings. If desired, no more than 1 teaspoon of butter or stick of margarine a day.
Mini Pistachio Thumbprint Cookies Recipe, For Your Best Health: The Mediterranean Diet (Still No. 1)
Among the most important news items I share in this newsletter are results of scientific studies on the benefits of olive oil and, in a larger context, the Mediterranean diet. I love to report on research that shows how this way of eating—and living—has positive impacts on heart and brain health and can help ward off serious chronic diseases including diabetes and dementia.
It’s also rewarding to see how the diet has been adopted here in the US and how many of our esteemed institutions, such as the American Heart Association and the Cleveland Clinic, recommend it. An annual survey that so many people appreciate reading is the U.S. News & World Report’s ranking of dietary plans or “Best Diets.” And for the seventh year in a row the Mediterranean diet triumphs in the top spot. I’ll detail the highlights of the magazine’s reasoning right after this delicious recipe for cookies you can enjoy guilt-free—in moderation, of course.
With a minimal amount of sugar, these cookies pack all the heart-healthy benefits of nuts, a key food—along with extra virgin olive oil—of the Mediterranean diet. Though sweets are the smallest food group on the Mediterranean diet food pyramid, we know that an occasional treat can help us stay on track with this healthful way of eating. This recipe shows that you don’t have to make huge sacrifices to enjoy it.
Ingredients
1 cup shelled pistachios
1-1/2 cups almond flour
1/2 cup granulated sugar
2 large egg whites
1/4 teaspoon sea salt
2 tablespoons extra virgin olive oil
1/2 teaspoon almond extract
1 teaspoon vanilla extract or paste
1/4 cup raspberry or apricot all-fruit (no sugar added) preserves, such as Polaner or St. Dalfour
Directions
Step 1
Preheat your oven to 350°F. Line two rimmed sheet pans with parchment paper. Use a spice or coffee bean grinder to pulverize the pistachios (you may need to do this is batches). Transfer to a large bowl along with the almond flour and sugar, and mix thoroughly.
Step 2
In a stand mixer or large bowl with a hand mixer, beat the egg whites and salt at a low speed until frothy, then increase the speed and beat until you get soft peaks. Briefly whip in the olive oil and the extracts. Fold the whites into the nut mixture with a large spatula until fully combined. The dough will be very firm.
Step 3
Using a 1-inch ice cream scoop or melon baller, make dough balls and evenly space them on the parchment-lined pans. Use your thumb to make an indentation in the top of each cookie, flattening the centers and then filling each with a half-teaspoon or so of preserves.
Step 4
Bake just until set, about 15 minutes, rotating the pans halfway through. Wait 5 minutes before transferring the cookies to a rack to cool. When completely cooled, store in an airtight tin.
Yields about 44 cookies
For Your Best Health
The Mediterranean Diet: Still No. 1
According to the U.S. News & World Report 2024 rankings, created in partnership with The Harris Poll and with input from a panel of leading health experts, the Mediterranean diet has once again taken the No. 1 spot in the Best Diets Overall category, thanks to its focus on diet quality and primarily plant-based foods. The Mediterranean diet also claimed the top spot in the categories Best Diets for Diabetes, Best Heart-Healthy Diets, Easiest Diets to Follow, Best Diets for Bone and Joint Health, Best Family-Friendly Diets, and Best Diets for Healthy Eating, and the No. 2 spot in the Best Weight Loss Diets and the Best Plant-Based Diets categories.
One of the reasons it’s both adoptable and adaptable is that there are so many cuisines to choose from when looking for recipes. Dishes that are popular in Turkey and Greece will offer different tastes than those from Italy, France, or Spain or from Morocco and other North African countries. But the unifying elements are the same: the emphasis on vegetables, fruits, extra virgin olive oil, nuts, whole grains, legumes, herbs, spices, and other plant-based foods that leave you feeling satisfied; minimal food processing; and a convivial atmosphere in the kitchen and at the table.
The Mediterranean diet also ranks high for what it leaves out:saturated fat, added sugars, and excess salt—all so prevalent in the typical American diet and so likely to leave you wanting more because foods with a low-nutrient profile are not truly satisfying. Eating them regularly also poses health risks. Eating a Mediterranean-style diet, on the other hand, translates to a longer life, a higher quality of life, and a lower risk of chronic diseases such as cancer, dementia, and heart disease.
The Mediterranean diet food pyramid is a great way to visualize the foods to focus on and how often to eat them. Whole grains, legumes, vegetables, fruit, and olive oil make up most of your daily intake. Seafood can be enjoyed a few times a week; animal proteins like poultry, eggs, cheese, and yogurt less often; and red meat less often still. But you also have a lot of leeway, so you don’t need to feel guilty about eating foods not on the pyramid. Nothing is totally eliminated, though you’re advised to eat foods like sugary desserts, butter, heavily processed foods like frozen meals, candy, and refined grains and oils sparingly.
Mediterranean Food Pyramid
To get started on the Mediterranean diet, or to more closely follow it, U.S. News & World Report suggests these tips:
Think of meat as your side dish and whole grains or vegetables as your main dish.
Look beyond Greek and Italian cuisines for inspiration—in all, 22 countries border the Mediterranean Sea!
As with any diet, do some advance meal planning so you won’t be tempted by convenience foods after a long day at work. For instance, cook up a batch of grains or lentils on the weekend to use for meals throughout the following week.
Make water your main source of hydration. Wine is considered optional and then only in moderation—one to two glasses per day for men and one glass per day for women.
Composed Roasted Beet Salad Recipe with Balsamic Vinegar, Spotlight on Whisks, Speaking More than One Language to Fight Alzheimer’s, and Protecting Against Falls at Every Age
Roasting brings out the flavors of autumn vegetables, making them exceptionally delicious—and the only thing better than drizzling them with extra virgin olive oil is also adding a few drops of rich balsamic vinegar from Modena, Italy. That’s why I’m so excited to announce my third collection of artisanal vinegars from the T. J. Robinson Curated Culinary Selections and the following recipe so that so well highlights my balsamic vinegar, Condimento Exclusivi Barili.
Also in this issue…If you’re looking for new pastimes as the weather changes, consider learning another language—a study review found that the brain reserves you’ll create could delay the arrival of dementia symptoms. And to protect physical health at every age, get to know simple steps to help prevent falls.
This is a great time of year to sample the savory sweetness of yellow beets. Roasting beets intensifies their surprising sweetness, a palate-pleasing contrast to the greens in this recipe. The bold flavors in this salad need just olive oil and balsamic vinegar to dress it, but you’ll need to bypass imposters and source true aceto balsamico from Italy—see the Healthy Ingredient Spotlight in my newsletter.
Ingredients
4 large yellow beets
2 tablespoons extra virgin olive oil, divided use, plus more for drizzling
1 tablespoon balsamic vinegar from Modena, plus more for drizzling
4 cups assorted salad greens
2 ounces Parmigiano-Reggiano shavings
1 ounce chopped hazelnuts
Directions
Preheat your oven to 400°F. Line a rimmed sheet pan with parchment paper. Trim the beets but don’t peel them, and cut into quarters. Transfer to the sheet pan and toss with 1 tablespoon olive oil. Roast until tender, up to one hour. Out of the oven, roll up the beets in the parchment paper and allow them to sit for 10 minutes; this makes it easy to now take off the peels. Toss them with the rest of the olive oil and the tablespoon of vinegar. Divide the greens among four plates and top with equal amounts of beets, cheese shavings, and hazelnuts. Drizzle with more olive oil and vinegar.
Yields 4 servings
Healthy Ingredient Spotlight
Authentic Balsamic Vinegar
As those of you who have already been enjoying the vinegars of the T. J. Robinson Curated Culinary Selections know, after years of requests from members of the Fresh-Pressed Olive Oil Club, I made it my mission to source the best artisanal vinegars on the planet. That meant distinguishing true aceto balsamico or balsamic vinegar from its many pretenders.
With so many bottles on store shelves labeled “balsamic,” it’s important to know how to choose correctly. First and foremost, the vinegar must be completely crafted in Modena, a city within the Emilia-Romagna region of Italy, according to exacting, centuries-old standards enforced by the local consortiums. Anything else is, quite simply, not balsamic vinegar. Beyond this, the ultimate quality of a Modena balsamic depends on the skill of the producer, including knowing what wood to pick for each period of aging.
When in Italy, I always look forward to walking through the pristine olive groves at Acetomodena, the producer of my collection’s balsamic vinegar.
A few different types of balsamic vinegars are available within the strict guidelines. There is Aceto Balsamico Tradizionale DOP (Denominazione di Origine Protetta or Protected Origin Denomination), which can take generations to make and is wildly expensive. That’s because it’s crafted exclusively from cooked grape must—all parts of the grapes are used—and aged for a minimum of 12 years and sometimes 25 years or even longer. A few ounces cost well over a hundred dollars, so it’s not used for cooking or making vinaigrettes but for drizzling sparingly on foods as a finishing touch.
The next is Aceto Balsamico di Modena IGP (Indicazione Geografica Protetta or protected geographical indication). It must be made from grape must and wine vinegar only and aged in wooden barrels for at least two months, but can be aged for as long as three years, which allows it to get sweeter and more harmonious as it achieves the perfect ratio of density to acidity. Many companies take the industrial route, rapidly boiling down the grape must, which often imparts the taste of burnt toast, and aging for the bare minimum.
Choosing the best vinegars for you can be as complex as choosing the best fresh-pressed olive oil. I love working with Gary Paton of Società Agricola Acetomodena in Modena and tasting just how nuanced “balsamic vinegar” can be, depending on the aging process.
The Acetomodena balsamic in my collection is a special IGP vinegar called Condimento Barili Exclusivi. The “condiment” designation allows producers more freedom to craft a vinegar that goes beyond strict IGP requirements with a taste akin to that of the Aceto Balsamico Tradizionale—it has the perfect balance of acidity, sweetness from grape must, and woodiness from the barrel aging.
Why you should have this vinegar in your kitchen: A pure balsamic vinegar, sweet and thick, is a culinary essential. It adds the perfect finish to cheeses, salads, grilled foods from vegetables to meat, and even desserts, like strawberries and figs.
Quick Kitchen Nugget
Whisks Aplenty
Having a few well-made whisks makes important cooking prep steps nearly effortless. But with so many sizes—and shapes—available, how do you know which ones you really need?
Start with a French whisk, long and narrow with numerous loops of wire, or tines, great for beating eggs and making egg-based sauces, custards, and curds. Add a balloon whisk, an overall large whisk that balloons to more of a ball shape at the end, for combining large volumes of dry or wet ingredients and whipping cream and egg whites if you don’t have a stand or hand mixer. Balloon whisks typically have fewer loops than smaller whisks so that ingredients don’t get caught in them. A very small mini-whisk is ideal for beating small quantities of vinaigrette, a single egg, or cocoa and milk for a cup of hot chocolate. There are more exotic shapes you can buy, like a flat whisk for reaching all around a saucepan and a coiled whisk (with a small oval of coiled wire at the end), if you’re an equipment lover.
Most important is whisk construction. Cheaply made whisks fail early on—the wires pop out of the handle or they just don’t have enough loops to be effective. Look for whisks made of high-quality, dishwasher-safe stainless steel. To avoid scratching nonstick saucepans, you’ll also want whisks made of silicone—just keep in mind that they’re more fragile and tend to require more arm work on your part.
For Your Best Health
Sprechen Sie Deutsch?
Or Italian, French, or Spanish? Today may be a great day to start! A new review conducted at UCLA and published in the Journal of Alzheimer’s Disease examined the numerous and often conflicting studies on whether regularly speaking two or more languages can help fight Alzheimer’s.
According to the review’s results, being bi- or multi-lingual does increase the brain’s cognitive reserve, a protective effect thought to stem from the executive control involved in managing multiple languages. The review acknowledged that findings in the various studies reviewed were not consistent when it came to factors like the age at which people should start learning another language, how proficient they need to be in it, or how often they need to use it. There also isn’t hard evidence that it can prevent Alzheimer’s, but most did find that the increased cognitive capacity and resilience of the brain’s frontal lobe from learning languages can delay the emergence of dementia symptoms by about 4 to 5 years. And that delay has a potentially significant impact on the course of the disease for those who get it. Another positive is that learning a new language can be fun in the here and now, especially with easy-to-access programs like Duolingo and Babbel, which have apps for your smartphone and free trials.
Fitness Flash
Protecting Against Falls At Every Age
We face not only mental but also physical perils as we age, and one of the most devastating can be a fall that breaks a bone, especially a hip. UNLV assistant professor, physical therapist, and board-certified neurological clinical specialist Jennifer Nash, DPT, CNS, explains it’s hard to recover from a hip fracture, and afterward, many people are unable to live on their own. More than 95% of hip fractures are caused by falling, usually by falling sideways. Women account for three-quarters of all hip fractures, often because of osteoporosis, which weakens bones and makes them more likely to break. Recovery from a broken hip can be grueling. It can land you in the hospital for a week and possibly a care facility afterward to continue healing.
During recovery, every activity of daily living, including any exercise, can be painful. That pain can create a vicious cycle when it comes to physical inactivity: The less you do, the less you will be able to do. Decreased activity leads to decreased strength and function, which leads to deconditioning, increased fear of activity, and decreased quality of life. This can all lead to even greater inactivity, Dr. Nash points out.
The answer is to do your best to prevent a fall in the first place with a plan based on guidelines from the National Council on Aging:
Participate in a good balance and exercise program. Try a community exercise program or get started on an individualized program with the help of a physical therapist.
Check in with your healthcare provider. Review any medications you’re taking for side effects that include dizziness. In fact, if different specialists have prescribed different medications for you, ask your primary care doctor or pharmacist to review them all for negative interactions. Have your blood pressure checked—some people experience dizziness from a blood pressure drop when they stand up from seated exercises or just from being in a chair.
Have your vision and hearing checked annually. Three components make up the body’s balance system: vision, proprioception (the ability to sense where you are with your feet), and the vestibular system (the inner ear). Dr. Nash says hearing is important for your balance. If you can’t hear someone coming up behind you, you might get startled and trip. Or maybe you can’t hear someone warning you about an uneven surface, which could lead to a fall. At a certain age, she says that, compared to single-focus lenses, bi-focal or tri-focal lenses can be problematic because they can lead you to look through the reading lens to climb stairs or uneven surfaces, and that can create depth-perception issues.
Create a safe home environment. Remove any and all tripping hazards like loose cords and clutter along the floor, even throw rugs. Improve your lighting, especially on stairs, which should have at least one railing. Add grab bars in key areas like the shower and near the toilet. Make sure there’s a night light on the path to the bathroom to lessen the chance of falling if you wake up in the middle of the night to go.
And if you ever do experience a fall and hit your head, call your doctor right away and ask about getting evaluated for a traumatic brain injury or TBI. Don’t wait for symptoms to appear.