Fresh-Pressed Olive Oil Club

Olive Oil Hunter News #270

Cheesy Onion Wraps Recipe, Spotlight on Vidalia Onions, Storing Onions, Are You Getting Enough B12 and The Benefits of 30 Minutes of Weekly Exercise

Sandwich wraps are handy alternatives to bread but can lack flavor. My cheesy onion wraps are so good you’ll be tempted to eat them right out of the pan (be sure to let them cool off first!). This issue of the newsletter looks at new research on the all-important vitamin B12 and why many people could be short. And for those who have a hard time fitting in exercise, I’m including details of a report that suggests 30 minutes per week rather than per day can still be helpful.

Olive Toast

  • Olive Toast with Goat Cheese Olive Toast

    This makes a satisfying lunch and a great appetizer for your next get-together. I love the tangy, fruity taste of sumac, a spice that’s finally getting the attention it deserves. If you’ve got the grill on, drizzle olive oil on the bread and toast over the coals. 

    Ingredients

    • 2 tablespoons extra virgin olive oil, plus more for drizzling
    • 1 teaspoon lemon zest
    • 2 tablespoons fresh lemon juice  
    • 1 medium garlic clove, grated
    • 1/2 teaspoon sumac, such as Wild Sumac
    • 1/4 teaspoon coarse sea salt
    • 1/4 teaspoon freshly ground black peppercorns like Vine-Ripened Black Peppercorns
    • 1/8 teaspoon peperoncino (Italian crushed red pepper flakes)
    • 4 ounces each pitted Castelvetrano and Kalamata olives
    • 2 tablespoons chopped fresh flat-leaf parsley
    • 8 baguette or crusty whole-grain bread slices
    • 8 ounces goat cheese at room temperature
    • 1/4 cup chopped walnuts

    Directions

    Step 1

    In a medium bowl, whisk together the olive oil, lemon zest and juice, garlic, sumac, salt, pepper, and peperoncino. Coarsely chop the olives and add to the bowl along with the parsley; let marinate for 30 minutes.

    Step 2

    When ready to assemble, toast the bread. Spread each slice with equal amounts of goat cheese, then top with the walnuts and the olive mixture. Drizzle with olive oil and serve.

    Yields 4 lunch or 8 appetizer servings

Healthy Ingredient Spotlight: Vidalia Onions

Healthy Ingredient Spotlight

Vidalia Onions

Grown in a limited area in Georgia, these onions are super sweet, thanks to their low sulfur content, which makes them less pungent and tear-inducing than other onion varieties. Their mild flavor profile means you can enjoy them raw, but they’re equally delicious cooked.

These onions are a good source of vitamin C, B6, and folate, potassium and manganese as well as quercetin, an antioxidant known for its anti-inflammatory properties, and fiber. They’re available from April to August; look for their trademark logo as well as their flatter shape. 

Quick Kitchen Nugget: Storing Onions

Quick Kitchen Nugget

Storing Onions

Vidalias have a high moisture content, and some experts recommend wrapping each one in a paper towel and storing them in the crisper drawer of your fridge. If you’re going to be using them in a few days, you can keep them on a rack in a cool, dry cabinet. But always keep any onions far away from potatoes because the ethylene gas produced by onions will cause your spuds to spoil prematurely. 

For Your Best Health: Are You Getting Enough B12?

For Your Best Health 

Are You Getting Enough B12?

Vitamin B12 is essential for helping your body make DNA, red blood cells, and healthy nerve tissue. While there are guidelines for daily intake, that amount may not actually be enough to protect the brain in later years. Researchers at the University of California San Francisco (UCSF) found that older adults with “normal” but lower levels of active B12 showed signs of slower thinking, delayed visual processing, and more damage to the brain’s white matter — the communication highways that help different brain regions work together. The findings raise the possibility that some people may be told their B12 status is fine while their brains are already showing early signs of strain.

For the study, published in Annals of Neurology, researchers enrolled 231 healthy older adults through the Brain Aging Network for Cognitive Health (BrANCH) study at UCSF. The participants had an average age of 71, and none had dementia or mild cognitive impairment. Their average blood B12 level was 414.8 pmol/L, far above the US minimum cutoff of 148 pmol/L. Instead of relying only on total B12, the researchers focused on the biologically active form of the vitamin, which may better reflect how much B12 the body can actually use. The study focused on older adults, a group that may be especially sensitive to lower B12 because absorption can become less efficient with age. Some medications, digestive conditions, and diets low in animal-based foods can also increase the risk of low B12.

After adjusting for age, sex, education, and cardiovascular risk factors, the team found that participants with lower active B12 had slower processing speed on cognitive tests. The effect was stronger with older age. They also had delayed responses to visual stimuli, pointing to slower visual processing and reduced brain signaling efficiency. 

MRI scans added another warning sign. Participants with lower active B12 had a higher volume of white matter lesions, which are areas of brain injury that have been linked to cognitive decline, dementia, and stroke risk. Even in this relatively healthy group, lower levels of active B12 were linked to slower thinking, slower visual processing, and more visible injury in the brain’s white matter. 

The work was led by senior author Ari J. Green, MD, of the UCSF Departments of Neurology and Ophthalmology and the Weill Institute for Neurosciences. Dr. Green and his colleagues said the results call attention to a possible weakness in current B12 guidelines. The minimum threshold used to define deficiency may not capture early functional changes in the nervous system.

“Previous studies that defined healthy amounts of B12 may have missed subtle functional manifestations of high or low levels that can affect people without causing overt symptoms,” said Dr. Green, noting that clear deficiencies of the vitamin are commonly associated with a type of anemia. “Revisiting the definition of B12 deficiency to incorporate functional biomarkers could lead to earlier intervention and prevention of cognitive decline.” 

The findings suggest that low but technically normal B12 could have broader effects than previously recognized. These levels could “impact cognition to a greater extent than what we previously thought and may affect a much larger proportion of the population than we realize,” said co-first author Alexandra Beaudry-Richard, MSc, who is currently completing her doctorate in research and medicine at the UCSF Department of Neurology and the Department of Microbiology and Immunology at the University of Ottawa.

“In addition to redefining B12 deficiency, clinicians should consider supplementation in older patients with neurological symptoms even if their levels are within normal limits,” she said. “Ultimately, we need to invest in more research about the underlying biology of B12 insufficiency, since it may be a preventable cause of cognitive decline.”

The UCSF findings do not prove that lower active B12 directly causes cognitive decline, and they do not mean every older adult should begin taking supplements without medical guidance. They do, however, suggest that the current definition of B12 deficiency may be too blunt for brain health.

Fitness Flash Icon: The Benefits of 30 Minutes of Weekly Exercise 

Fitness Flash

The Benefits of 30 Minutes of Weekly Exercise 

Current health recommendations suggest exercising for at least 2.5 hours each week, with 5 hours considered even better. For many people, that target can seem overwhelming. Here’s music to their ears: According to researchers at the Norwegian University of Science and Technology (NTNU), you may not need hours at the gym to boost your health after all. Studies from the past two decades suggest that just 30 minutes of high-intensity exercise per week can improve health. That works out to roughly 4.3 minutes per day or about 10 minutes every other day. 

The important part is intensity. The activity needs to be strenuous enough to leave you noticeably out of breath. If you use a heart rate monitor, researchers say your heart rate should reach about 85 percent of your maximum. However, special equipment is not necessary. A simple way to judge intensity is by how difficult it is to talk. You should still be able to speak in short sentences, but you should not be able to sing or carry on a continuous conversation comfortably.

“The biggest reported challenge regarding exercise is lack of time. But with intense, short workouts, this is no longer a valid excuse,” said Ulrik Wisløff, a professor at NTNU and head of CERG, a research group that studies the health effects of exercise. Researchers say even a small amount of high-intensity activity can improve cardiovascular fitness, which plays a major role in long-term health. “Cardiovascular fitness is the best indicator of current and future health. Good cardio fitness reduces the risk of over 30 lifestyle diseases as well as premature death by 40 to 50 percent,” explained Wisløff.

CERG first documented these effects in a 2006 study that analyzed health information from 60,000 people. Since then, additional large studies from Norway and other countries have reported similar findings.

Intense home exercise for heart health

Rather than doing one intense 30-minute workout each week, it’s best to spread out the sessions, said Wisløff. Blood pressure and blood sugar control improve for 24 to 48 hours after a workout that pushes you hard enough to become breathless for several minutes. Because of these short-term benefits, divide exercise across two to four days per week whenever possible.

That does not necessarily mean sprinting at full speed or using the highest resistance setting on an exercise bike. “Your own personal fitness level determines what gives you a high heart rate,” Wisløff said. “If you are not very fit, simply taking a brisk walk may be enough. Having said that, you need to walk fast enough that you get quite out of breath. You can then increase the intensity as your fitness improves. Short intervals are effective. For example, this could be bursts of 45 seconds with 15-second breaks. Or like in Tabata workouts, with intense 20-second intervals interspersed with 10-second breaks. Otherwise, 4×4 intervals are recognized as highly effective for increasing oxygen uptake.”

“Fitness is something you have to maintain. Cardio fitness and strength decline quickly when not maintained, especially as you get older,” said Atefe R. Tari, PhD, a researcher and head of CERG’s initiative on exercise and brain health. Strength training is also considered important, particularly for middle-aged and older adults. “We know that strength training is important, especially for middle-aged and older adults. There is limited research on how strength training affects lifespan, but a HUNT study exploring this is due to be published soon,” said Wisløff. “Physical health and brain health are closely linked, and cardio fitness is key here as well. Exercise leads to the formation of new brain cells,” added Dr. Tari.

Wisløff and Tari are now encouraging Norwegian health authorities to revise the country’s official exercise recommendations, arguing that exercise intensity should receive greater emphasis.

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Olive Oil Hunter News #269

Olive Toast Recipe, Spotlight on Castelvetrano Olives, Storing Bread, Weight Loss Tweaks and Walking and Weight Loss

Move over, avocado. There’s a new toasty trend taking shape and it starts with olives. The best part? You can get creative with toppings—yes, even add a layer of avo if you like. I’m also sharing new findings about effective weight loss and how to keep it off.

Olive Toast

  • Olive Toast with Goat Cheese Olive Toast

    This makes a satisfying lunch and a great appetizer for your next get-together. I love the tangy, fruity taste of sumac, a spice that’s finally getting the attention it deserves. If you’ve got the grill on, drizzle olive oil on the bread and toast over the coals. 

    Ingredients

    • 2 tablespoons extra virgin olive oil, plus more for drizzling
    • 1 teaspoon lemon zest
    • 2 tablespoons fresh lemon juice  
    • 1 medium garlic clove, grated
    • 1/2 teaspoon sumac, such as Wild Sumac
    • 1/4 teaspoon coarse sea salt
    • 1/4 teaspoon freshly ground black peppercorns like Vine-Ripened Black Peppercorns
    • 1/8 teaspoon peperoncino (Italian crushed red pepper flakes)
    • 4 ounces each pitted Castelvetrano and Kalamata olives
    • 2 tablespoons chopped fresh flat-leaf parsley
    • 8 baguette or crusty whole-grain bread slices
    • 8 ounces goat cheese at room temperature
    • 1/4 cup chopped walnuts

    Directions

    Step 1

    In a medium bowl, whisk together the olive oil, lemon zest and juice, garlic, sumac, salt, pepper, and peperoncino. Coarsely chop the olives and add to the bowl along with the parsley; let marinate for 30 minutes.

    Step 2

    When ready to assemble, toast the bread. Spread each slice with equal amounts of goat cheese, then top with the walnuts and the olive mixture. Drizzle with olive oil and serve.

    Yields 4 lunch or 8 appetizer servings

Healthy Ingredient Spotlight: Castelvetrano Olives

Healthy Ingredient Spotlight

Castelvetrano Olives

Castelvetranos olives

If you’re someone who adores fresh-pressed olive oil yet shies away from olives, Castelvetranos are for you. Known as Nocellara del Belice, this varietal from the Valle del Belice region of Sicily is known for its buttery flavor and smooth skin and is a great source of healthy monounsaturated fats. 

Quick Kitchen Nugget: Storing Bread

Quick Kitchen Nugget

Storing Bread

Grandma’s bread box was a great way to keep a loaf fresh. The modern-day innovation is a linen bread bag, available for crusty round loaves or baguettes. The fabric helps keep the crust firm without drying out the insides…but only for 2 or 3 days. If you need longer storage, slice the loaf and freeze.   

For Your Best Health: Weight Loss Tweaks

For Your Best Health 

Weight Loss Tweaks

A study led by the Barcelona Institute for Global Health (ISGlobal) and published in the International Journal of Behavioral Nutrition and Physical Activity found that two habits are linked to a lower body mass index (BMI) over time: extending the overnight fasting period and eating breakfast early. Scientists think this is because eating earlier aligns better with the body’s internal clock. On the other hand, skipping breakfast as part of intermittent fasting didn’t offer the same advantage and may even be tied to unhealthy habits. 

The findings are based on data from more than 7,000 adults between the ages of 40 and 65 who are part of the GCAT | Genomes for Life cohort, led by the Germans Trias i Pujol Research Institute (IGTP) in Barcelona. In 2018, participants provided details about their height, weight, meal timing, lifestyle habits, and socioeconomic background through questionnaires. Five years later, in 2023, more than 3,000 of these individuals returned for follow-up assessments. Researchers recorded updated measurements and collected new survey data, allowing them to track changes and identify patterns over time.

“Our results, in line with other recent studies, suggest that extending the overnight fast could help maintain a healthy weight if accompanied by an early dinner and an early breakfast. We think this may be because eating earlier in the day is more in line with circadian rhythms and allows for better calorie burning and appetite regulation, which can help maintain a healthy weight. However, it is too soon to draw definitive conclusions, so recommendations will have to wait for more robust evidence,” explained Luciana Pons-Muzzo, MPH, researcher at ISGlobal at the time of the study and currently at IESE Business School.

When researchers compared results by gender, they found notable differences. Women generally had lower BMI, followed the Mediterranean diet more closely, and were less likely to drink alcohol. At the same time, they reported poorer mental health and were more often responsible for household or family supervision.

Using a method called cluster analysis, the team grouped participants with similar characteristics. One small group of men stood out. These individuals typically ate their first meal after 2 pm and fasted for about 17 hours. Compared to others, they were more likely to smoke and drink alcohol, less physically active, and less likely to follow the Mediterranean diet. They also tended to have lower levels of education and higher rates of unemployment. Researchers did not observe a similar pattern among women.

“There are different ways of practicing what is known as intermittent fasting and our study relates to one of them, which is overnight fasting. What we observed in a subgroup of men who do intermittent fasting by skipping breakfast is that this practice has no effect on body weight. Other intervention studies in participants with obesity have shown that this tactic is no more effective than reducing calorie intake for reducing body weight in the long term,” said Camille Lassale, PhD, ISGlobal researcher and senior co-author of the study.

“Our research is part of an emerging field of research known as ‘chrononutrition’, which focuses not only on analyzing what we eat, but also the times of day and the number of times we eat,” says Anna Palomar-Cros, PhD, researcher at ISGlobal at the time of the study and currently at IDIAP Jordi Gol. “At the basis of this research is the knowledge that unusual food intake patterns can conflict with the circadian system, the set of internal clocks that regulate the cycles of night and day and the physiological processes that must accompany them.” 

This study builds on earlier ISGlobal research in chrononutrition, which found that eating dinner and breakfast earlier in the day is associated with a lower risk of cardiovascular disease and type 2 diabetes, reinforcing the idea that meal timing plays a meaningful role in long-term health.

Fitness Flash Icon: Walking and Weight Loss

Fitness Flash

Walking and Weight Loss

Many weight loss programs encourage people to walk more each day, but there has been limited evidence showing whether increasing daily steps actually helps people lose weight while dieting. It’s also unclear whether walking more can help people maintain weight loss over time and, if so, what step count may be most effective.

“The most important—and greatest—challenge when treating obesity is preventing weight regain,” explained Professor Marwan El Ghoch, MD, of the Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy. “Around 80% of people with overweight or obesity who initially lose weight tend to put some or all of it back on again within three to five years. The identification of a strategy that would solve this problem and help people maintain their new weight would be of huge clinical value.”

Woman walking dog for weight loss

To find such a strategy, Dr. El Ghoch and colleagues from Italy and Lebanon carried out a systematic review and meta-analysis of previous studies focused on walking and weight management and presented their soon-to-be-published analysis at this year’s European Congress on Obesity in Istanbul, Turkey.

The researchers reviewed 18 randomized controlled trials. Of those, 14 studies involving 3,758 adults were included in the final meta-analysis. Participants had an average age of 53 years and an average BMI of 31 kg/m2. The studies included people from several countries, including the UK, US, Australia, and Japan. The trials compared 1,987 participants enrolled in lifestyle modification (LSM) programs with 1,771 people in control groups who were either dieting without additional support or receiving no treatment.

The lifestyle modification programs combined dietary guidance with recommendations to walk more and track daily steps. These programs included an initial weight loss phase followed by a maintenance phase designed to help participants keep the weight off long term. Researchers measured participants’ daily step counts at the beginning of the studies, after the weight loss phase (average duration of 7.9 months), and after the maintenance phase (average duration of 10.3 months). At the start of the trials, both groups had similar activity levels. Participants in the LSM group averaged 7,280 steps per day, while those in the control group averaged 7,180 steps daily.

The control group did not significantly increase daily walking and did not experience weight loss during the studies. Participants in the LSM programs, however, increased their daily step count to an average of 8,454 steps by the end of the weight loss phase. During that time, they lost an average of 4.39% of their body weight, equal to roughly 4 kg.

Participants largely maintained their higher activity levels throughout the maintenance phase, averaging 8,241 steps per day by the end of the studies. They also kept off most of the weight they had lost, with an average long-term weight loss of 3.28%, or about 3 kg. Further analysis revealed a clear connection between higher daily step counts and reduced weight regain. Researchers found that people who increased their steps during the weight loss phase and continued that level of activity afterward were more successful at maintaining their weight loss. 

Interestingly, walking more was not linked to greater weight loss during the initial dieting phase. Researchers believe this may be because factors such as calorie reduction have a stronger effect on short-term weight loss.

Dr. El Ghoch said the findings show that lifestyle modification programs can support meaningful long-term weight loss. “Participants should be always encouraged to increase their step count to approximately 8,500 a day during the weight loss phase and sustain this level of physical activity during the maintenance phase to help prevent them from regaining weight,” he said. “Increasing the number of steps walked to 8,500 each day is a simple and affordable strategy to prevent weight regain.”

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Olive Oil Hunter News #268

Marinated Mozzarella Pearls Recipe, Spotlight on Mozzarella, Storing Jars, The Fat Conundrum, and The Smarter Mediterranean Diet

It’s not quite summer and I’m already looking for recipes that don’t involve turning on the oven! This mozzarella dish fits the bill. It couldn’t be more flavorful…or simpler. The cheese is the perfect foil for fresh-pressed olive oil—I know you’ll be serving it from now through autumn! One of the two new studies I’m sharing reveals that excess weight poses different threats for women and men, while the other presents a possible solution for everyone: an approach called the “smarter” Mediterranean diet. Read on for the details.

Marinated Mozzarella Pearls

  • Marinated Mozzarella Pearls Marinated Mozzarella Pearls

    Add zest to mozzarella with this flavorful marinade. Pearls are cheese balls about the size of cherry tomatoes. Serve them as a finger food or pair with tomatoes for a first course. 

    Ingredients

    • 1 medium lemon
    • 1 garlic clove
    • 1/4 cup finely chopped mix of fresh parsley and basil leaves
    • 1/4 teaspoon crushed red pepper flakes, or more to taste
    • 1/2 cup extra virgin olive oil
    • 1/2 teaspoon coarse sea salt 
    • 16 ounces mozzarella pearls

    Directions

    Step 1

    Use a Microplane set over a medium bowl to zest the lemon (reserve the rest of the lemon for another recipe) and grate the garlic. Add the herbs, red pepper, olive oil, and salt if using and whisk well.

    Step 2

    Place the mozzarella into a half-pint lidded jar. Drizzle the olive oil mixture over the pearls and let marinate on the counter for 30 minutes. If not eating right away, cover and refrigerate (bring to room temperature before serving). 

    Serves 8

Healthy Ingredient Spotlight: Fresh Mozzarella 

Healthy Ingredient Spotlight

Fresh Mozzarella 

Fresh mozzarella and tomatoes

Handcrafted fresh mozzarella, now available in many food markets, is a versatile cheese, ready to be enjoyed cold or melted in hot dishes. True Italian mozzarella is mozzarella di bufala, or mozzarella made from milk of the Italian Mediterranean buffalo. In the US, it is almost always made from cow’s milk, though a handful of artisanal makers are raising buffalo to produce more authentic varieties and some Italian makers export the real thing.

Debunking cheese’s negative health rap, research published in the journal Advances in Nutrition found moderate evidence suggesting that eating cheese doesn’t increase the risk of cardiovascular diseases and may even offer some protection from these ills. Fresh mozzarella, in particular, is considered one of the healthier cheeses, due to its low fat and sodium content along with 7 grams of protein and over 200 mg of calcium per ounce.

Quick Kitchen Nugget: Storing Jars

Quick Kitchen Nugget

Storing Jars

With the move away from plastics, there are many glass options for storing food. Round clip top jars made by companies including Kilner and Weck are cylindrical containers with a hinged metal clamp and replaceable rubber seal. Great for storing dry staples like flour, grains, pasta, even teas, they’re also perfect for marinating and pickling vegetables. Mason jars go one step further—thanks to their tempered glass, they can withstand the heat of boiling water, making them ideal for canning. To meet kitchen needs, consider a range of sizes: half-pint (1 cup), pint (2 cups), quart (4 cups), and half-gallon (8 cups).

For Your Best Health: The Fat Conundrum

For Your Best Health 

The Fat Conundrum

New findings presented by a research team from Dokuz Eylul University in Izmir, Turkey at this year’s European Congress on Obesity (ECO) highlight clear differences in how obesity affects men and women. 

“Our findings reveal intriguing differences in the way men and women respond to obesity,” said lead author Dr. Zeynep Pekel. “They show just how important gender-specific research is. Not only are sex differences a powerful player in the pathology and course of obesity, but our results indicate that such differences could be a stepping stone toward finding targeted, sex-based therapies to help in the management of people living with obesity.”

Their findings showed that men with obesity are more likely to accumulate abdominal (visceral) fat. This type of fat surrounds internal organs and is strongly linked to serious heart and metabolic conditions. They had a slightly higher body mass index (BMI) than women (37.5 vs 36.0 kg/m²), but their waist circumference was much larger (120 vs 108 cm), and their systolic blood pressure was also higher (128 vs 122 mmHg), two factors linked to increased risk of cardiovascular disease and diabetes. The men also had significantly higher levels of liver enzymes (ALT and GGT), triglycerides, and creatinine. These findings point to a greater likelihood of liver-related and metabolic complications.

Women with obesity, on the other hand, had higher total cholesterol (215 vs 203 mg/dL) and LDL or “bad” cholesterol (130 vs 123 mg/dL). They typically store more fat beneath the skin and showed higher levels of inflammatory markers, including erythrocyte sedimentation rate, C-reactive protein, and platelet count, raising the risk of heart disease and type 2 diabetes. 

“It’s still early days and these findings need to be confirmed in other patient groups, but they offer important insight into how obesity may affect men and women differently,” said Dr. Pekel. “These differences are likely influenced by biological factors such as hormones, immune responses, and fat distribution. Our next steps are to validate these findings in larger populations, better understand the biological processes behind these differences, and explore how these patterns relate to clinical risk.”

Fitness Flash Icon: The Smarter Mediterranean Diet 

Fitness Flash

The Smarter Mediterranean Diet 

Mediterranean foods

The Mediterranean diet is already famous for its heart and metabolic benefits. Now a large European study called the PREDIMED-Plus Trial revealed that a lower-calorie Mediterranean diet may work even better against type 2 diabetes when paired with three realistic upgrades: eating fewer calories, moving more, and getting professional support for weight loss.

The trial found that this more structured version of Mediterranean living reduced the risk of developing type 2 diabetes by 31% over six years. Participants also lost more weight (3.3 kg), reduced abdominal fat more effectively, and reduced waist circumference by 3.6 cm, compared to those following a standard Mediterranean diet alone. 

In real world terms, the researchers estimated that the program prevented about three cases of type 2 diabetes for every 100 participants. For a condition affecting hundreds of millions of people globally, that kind of prevention could add up quickly if applied broadly among people at elevated risk.

“Diabetes is the first solid clinical outcome for which we have shown — using the strongest available evidence — that the Mediterranean diet with calorie reduction, physical activity, and weight loss is a highly effective preventive tool,” said Miguel Ángel Martínez-González, Professor of Preventive Medicine and Public Health at the University of Navarra, Adjunct Professor of Nutrition at Harvard University, and one of the principal investigators of the project. “Applied at scale in at-risk populations, these modest and sustained lifestyle changes could prevent thousands of new diagnoses every year. We hope soon to show similar evidence for other major public health challenges.”

“The Mediterranean diet acts synergistically to improve insulin sensitivity and reduce inflammation. With PREDIMED-Plus, we demonstrate that combining calorie control and physical activity enhances these benefits,” explained Miguel Ruiz-Canela, Professor and Chair of Preventive Medicine and Public Health Department at the University of Navarra’s School of Medicine and first author of the study. “It is a tasty, sustainable, and culturally accepted approach that offers a practical and effective way to prevent type 2 diabetes — a global disease that is, to a large extent, avoidable.”

The project is the largest nutrition trial conducted in Europe and involved the University of Navarra along with more than 200 researchers from 22 other Spanish universities, as well as hospitals and research centers. The work was carried out in more than 100 primary care centers within Spain’s National Health System.

Since the PREDIMED-Plus diabetes findings were prepared, related research has continued to strengthen the broader picture. A PREDIMED-Plus body composition analysis published in JAMA Network Open found that the energy-reduced Mediterranean diet plus physical activity helped reduce total and visceral fat while slowing age-related loss of lean mass in older adults with overweight or obesity and metabolic syndrome. That matters because visceral fat and declining muscle are closely tied to cardiometabolic risk.

More recent PREDIMED-Plus work has also explored how sedentary time may affect cardiovascular health. A 2026 study in BMC Cardiovascular Disorders reported that replacing sedentary time with physical activity was associated with favorable five-year changes in high-sensitivity troponin T, a blood marker related to heart stress, although the pattern was not consistent across all atrial fibrillation–related biomarkers.

A 2026 analysis from the original PREDIMED trial also highlighted the possible importance of food quality within the diet. Participants with higher cumulative intake of extra virgin olive oil had a lower risk of a broad cardiovascular outcome, while common olive oil showed weaker associations. The finding supports a practical message for readers: the Mediterranean diet is not only about eating less or eating more plants. The type and quality of fats may matter too.

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Olive Oil Hunter News #267

Double Strawberry Mousse Recipe, Spotlight on Strawberries, Buying and Storing Strawberries, The Impact of Carbs and Lowering Your Disease Risk

As farmers’ markets pop up around the country, look for fresh strawberries ripe for turning into luscious desserts. This mousse is sinfully rich, yet so easy to whip up. Whole foods are crucial to a healthy diet, and the first study I’m sharing shows what happens when we eat too many refined carbs. The second sheds new light on the importance of exercise intensity.

Double Strawberry Mousse

  • Double strawberry mousse Double Strawberry Mousse

    This dessert features strawberries in the mousse and in the topping. The berries are first macerated — tossed with sugar and allowed to sit — to draw out and intensify the fruit’s flavors.

    Ingredients

    • 1 1/2 pounds fresh strawberries 
    • 2 tablespoons granulated sugar
    • 1 tablespoon extra virgin olive oil
    • 1 1/2 cups heavy cream
    • Optional: 1/3 cup confectioners’ sugar 

    Directions

    Step 1

    Hull the strawberries, then dice them and place in a large glass bowl. Add the granulated sugar and toss well; set aside for 30 minutes. Drizzle on the olive oil and mix well. Reserve 1/2 cup of the berries, cover, and refrigerate. Place the rest in a food processor and run the machine until the berries are puréed. You should have about 1-1/2 cups.

    Step 2

    Place the heavy cream in the bowl of a stand mixer or a large bowl with a hand mixer. Beat on low speed, then gradually increase to high. Whip until the cream reaches medium (not stiff) peaks, then use a spatula to fold in the strawberry purée. Taste and add the confectioners’ sugar if desired. Serve right away or refrigerate the mousse in the mixing bowl for up to 4 hours — it will firm up more as it chills.

    Step 3

    To serve, spoon equal portions of the mousse into 8 goblets or bowls and garnish with equal amounts of the reserved berries.

    Serves 8

Healthy Ingredient Spotlight: Strawberries

Healthy Ingredient Spotlight

Strawberries

Strawberries are packed with essential vitamins, minerals, fiber, and phytochemicals, including anthocyanins, which give them their vivid hue, and other antioxidants to protect against oxidative stress. A study published in the journal Nutrition, Metabolism and Cardiovascular Diseases found that eating about 2 cups of strawberries a day improves heart health and cognition in older adults. 

There is one caveat. According to the Environmental Working Group, strawberries have high levels of pesticides including “forever chemicals” (PFAS) and fungicides—they’re often ranked at the top of the Group’s “Dirty Dozen” list of most affected fruits and vegetables. Because of this, buy organic whenever you can to reduce your exposure to substances linked to cancer, hormone disruption, and brain toxicity. 

fresh strawberries on the vine
Quick Kitchen Nugget: Buying and Storing Strawberries 

Quick Kitchen Nugget

Buying and Storing Strawberries 

Look for bright red strawberries, with bright green caps, and free of moldy spots. If you’re buying berries packed in plastic boxes, be sure to turn them over and check the underside. At home, refrigerate your berries if not using right away, but don’t wash them ahead of time, which could increase the risk for mold. Store packaged berries upside down — this puts the ventilation slots on top, allowing better air circulation. 

For Your Best Health: The Impact of Carbs

For Your Best Health 

The Impact of Carbs

Bread has long been a dietary cornerstone, sustaining societies for generations. It is deeply woven into everyday life. Carbohydrates such as bread, rice, and noodles are consumed daily around the world, yet their role in obesity and metabolism has not been explored thoroughly. With obesity rates continuing to climb, researchers are beginning to question whether this reliance on staple carbohydrates still makes sense in modern diets. While many people believe that “bread makes you gain weight” or that “carbohydrates should be limited,” it has been unclear whether the issue lies in the foods themselves or in how people choose and consume them.

To better understand these questions, a research team led by Professor Shigenobu Matsumura at Osaka’s Graduate School of Human Life and Ecology in Japan studied how carbohydrates influence eating behavior and metabolism in mice. The researchers examined whether mice preferred foods like wheat, bread, and rice over standard chow, and how these choices affected body weight and energy use. The animals were divided into several feeding groups, including Chow, Chow + Bread, Chow + Wheat flour, Chow + Rice flour, High-fat diet (HFD) + Chow, and HFD + Wheat flour. The team tracked changes in body weight, energy expenditure, blood metabolites, and liver gene expression.

The findings showed that mice strongly favored carbohydrate-rich foods and stopped eating their standard chow altogether. Even though their total calorie intake did not increase significantly, both body weight and fat mass went up. Mice that consumed rice flour gained weight in a similar way to those that ate wheat flour. In contrast, mice given a High-fat diet (HFD) + Wheat flour gained less weight than those on a High-fat diet (HFD) + Chow. “These findings suggest that weight gain may not be due to wheat-specific effects, but rather to a strong preference for carbohydrates and the associated metabolic changes,” said Professor Matsumura.

Further analysis revealed higher levels of fatty acids in the blood and lower levels of essential amino acids. In the liver, fat accumulation increased, along with the activity of genes linked to fatty acid production and lipid transport. When wheat flour was removed from the diet, both body weight and metabolic abnormalities improved quickly. This suggests that moving away from a wheat-heavy diet and toward a more balanced one may help regulate body weight more effectively.

“Going forward, we plan to shift our research focus to humans to verify the extent to which the metabolic changes identified in this study apply to actual dietary habits,” said Professor Matsumura. “We also intend to investigate how factors such as whole grains, unrefined grains, and foods rich in dietary fiber, as well as their combinations with proteins and fats, food processing methods, and timing of consumption, affect metabolic responses to carbohydrate intake. In the future, we hope this will serve as a scientific foundation for achieving a balance between ‘taste’ and ‘health’ in the fields of nutritional guidance, food education, and food development.”

Fitness Flash Icon: Lowering Your Disease Risk

Fitness Flash

Lowering Your Disease Risk

Just a few minutes of getting out of breath each day could significantly cut your risk of major diseases including heart disease, dementia, and diabetes. A large study of nearly 100,000 people published in the European Heart Journal found that it’s not just how much you move, but how intensely you move that matters. Short bursts of vigorous activity—like rushing for a bus or climbing stairs quickly—were linked to striking reductions in disease risk, especially for inflammatory conditions like arthritis, serious cardiovascular problems such as heart attack and stroke, and dementia.

To explore this connection, researchers compared participants’ overall physical activity levels with how much of that activity was vigorous, then tracked their risk of developing eight major diseases over time. The study was led by an international team that included Professor Minxue Shen from the Xiangya School of Public Health at Central South University in Hunan, China. “We know that physical activity reduces the risk of chronic disease and premature death, and there is growing evidence that vigorous activity provides greater health benefits per minute than moderate activity,” he said. “But questions remain about the importance of intense activity versus total physical activity. For example, if two people do the same total amount of activity, does the person who exercises more vigorously gain greater health benefits? And if someone has limited time, should they focus on exercising harder rather than longer?”

Participants, all part of the UK Biobank study, wore wrist-based accelerometers for one week. These devices captured detailed movement patterns, including short bursts of vigorous activity that people might not remember or report. Researchers used this data to calculate both total activity and the share that was intense enough to cause breathlessness.

The team then compared these measurements with participants’ likelihood of dying or developing eight serious conditions over the next seven years: major cardiovascular disease, irregular heartbeat, type 2 diabetes, immune-mediated inflammatory diseases, liver disease, chronic respiratory diseases, chronic kidney disease, and dementia.

The results showed that people who devoted a larger portion of their activity to vigorous movement had much lower risks across all conditions studied. Compared with those who did no vigorous activity, individuals with the highest levels saw a 63% lower risk of dementia, a 60% lower risk of type 2 diabetes, and a 46% lower risk of death. These benefits were observed even when the total time spent on vigorous activity was relatively small.

Couple working out and sweating

The researchers also found that intensity played a larger role for certain diseases. For inflammatory conditions such as arthritis and psoriasis, intensity appeared to be the key factor in lowering risk. In contrast, for diseases like diabetes and chronic liver disease, both how long people were active and how hard they exercised were important.

“Vigorous physical activity appears to trigger specific responses in the body that lower-intensity activity cannot fully replicate,” Professor Shen said. “During vigorous physical activity — the kind that makes you feel out of breath — your body responds in powerful ways. Your heart pumps more efficiently, your blood vessels become more flexible, and your body improves its ability to use oxygen. Vigorous activity also appears to reduce inflammation. This may help explain why we saw strong associations with inflammatory conditions such as psoriasis and arthritis. It may also stimulate chemicals in the brain that help keep brain cells healthy, which could help explain the lower risk of dementia.

“Our findings suggest that making some of your physical activity vigorous can provide substantial health benefits. This doesn’t require going to the gym. Adding short bursts of activity that make you slightly breathless into daily life, like taking the stairs quickly, walking fast between errands, or playing actively with children, can make a real difference. Even 15 to 20 minutes per week of this kind of effort — just a few minutes a day — was linked to meaningful health benefits.

“Current guidelines generally focus on the amount of time spent being active per week. Our findings suggest that the composition of that activity matters and matters differently depending on which diseases you’re trying to prevent. This could open the door to more personalized physical activity recommendations based on an individual’s specific health risks,” he said, adding, “Vigorous activity may not be safe for everyone, especially older adults or people with certain medical conditions. For them, any increase in movement is still beneficial, and activity should be tailored to the individual.”

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