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The Effects of the MIND and Mediterranean Diets on Parkinson’s Disease

Adapted from an article by Dr. Rebecca Gilbert, American Parkinson’s Disease Association, May 4, 2021

New research into the best diets for Parkinson’s Disease (PD) reveals the Mediterranean and MIND diets may be associated with later age of onset of PD. Components of a Mediterranean diet include vegetables; fruits; whole grains; legumes such as beans, peas, and lentils; nuts; low-fat proteins, such as fish and poultry; and olive oil.

Another diet, known as the Dietary Approaches to Stop Hypertension (DASH) diet, was designed to help treat and prevent high blood pressure and emphasizes many of the same principles as the Mediterranean diet. More recently, experts suggested a combination of the Mediterranean and DASH diets, meant to maximize cognitive benefits. It is entitled the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet. Components of the MIND diet include green, leafy vegetables; all other vegetables; berries; whole grains; beans; nuts; poultry; fish; red wine; and olive oil.

The principles of the MIND diet are very similar to the Mediterranean diet, with some notable additions. The MIND diet recommends green leafy vegetables such as spinach and kale as the first choice over other vegetables. Berries (such as blueberries) are specifically promoted, as opposed to fruit in general. A small amount of red wine daily is also encouraged. (Please discuss this with your doctor.)

Why do these diets work?

The scientific underpinnings as to why these diets affect brain health are not fully understood and likely consist of a combination of different positive benefits—some of which have been established and others that have not. It is possible that the established heart benefits of the diets drive some of the brain health benefits. That is, the diets promote healthy hearts and clean blood vessels and therefore support excellent blood flow to the brain. It is well established that vascular disease in the brain can contribute to cognitive decline as well as the motor symptoms of Parkinsonism. Therefore, ensuring that the brain achieves good blood flow has positive benefits on brain health for everyone, especially those who have a disease such as PD.

In addition, specific components of the foods encouraged in these diets may work on the cellular level to protect neurons from cell death or decrease neuroinflammation. But knowing which elements are conferring the benefit is not straightforward. To date, researchers have not been able to identify a specific nutritional supplement that achieved the type of benefits in clinical trial demonstrated in this diet study. Currently, therefore, the best way to ingest the nutrients that protect the brain is through a comprehensive dietary plan and not by taking a defined group of supplements.

Takeaways

  • A new study has demonstrated that the MIND and Mediterranean diets are associated with a delay in onset of PD symptoms
  • Both of these diets emphasize vegetables, fruits, whole grains, legumes, nuts, and olive oil
  • The MIND diet adds green leafy vegetables and berries as important elements

Reference: Metcalfe-Roach A, Yu A, Golz E, et al. MIND and Mediterranean diets associated with later onset of Parkinson’s Disease. Mov Disord. 2021;36(4):977-984. doi: 10.1002/mds.28464.