Cheesy Onion Wraps Recipe, Spotlight on Vidalia Onions, Storing Onions, Are You Getting Enough B12 and The Benefits of 30 Minutes of Weekly Exercise
Sandwich wraps are handy alternatives to bread but can lack flavor. My cheesy onion wraps are so good you’ll be tempted to eat them right out of the pan (be sure to let them cool off first!). This issue of the newsletter looks at new research on the all-important vitamin B12 and why many people could be short. And for those who have a hard time fitting in exercise, I’m including details of a report that suggests 30 minutes per week rather than per day can still be helpful.
Olive Toast
Olive ToastThis makes a satisfying lunch and a great appetizer for your next get-together. I love the tangy, fruity taste of sumac, a spice that’s finally getting the attention it deserves. If you’ve got the grill on, drizzle olive oil on the bread and toast over the coals.
Ingredients
- 2 tablespoons extra virgin olive oil, plus more for drizzling
- 1 teaspoon lemon zest
- 2 tablespoons fresh lemon juice
- 1 medium garlic clove, grated
- 1/2 teaspoon sumac, such as Wild Sumac
- 1/4 teaspoon coarse sea salt
- 1/4 teaspoon freshly ground black peppercorns like Vine-Ripened Black Peppercorns
- 1/8 teaspoon peperoncino (Italian crushed red pepper flakes)
- 4 ounces each pitted Castelvetrano and Kalamata olives
- 2 tablespoons chopped fresh flat-leaf parsley
- 8 baguette or crusty whole-grain bread slices
- 8 ounces goat cheese at room temperature
- 1/4 cup chopped walnuts
Directions
Step 1
In a medium bowl, whisk together the olive oil, lemon zest and juice, garlic, sumac, salt, pepper, and peperoncino. Coarsely chop the olives and add to the bowl along with the parsley; let marinate for 30 minutes.
Step 2
When ready to assemble, toast the bread. Spread each slice with equal amounts of goat cheese, then top with the walnuts and the olive mixture. Drizzle with olive oil and serve.
Yields 4 lunch or 8 appetizer servings
Healthy Ingredient Spotlight
Vidalia Onions
Grown in a limited area in Georgia, these onions are super sweet, thanks to their low sulfur content, which makes them less pungent and tear-inducing than other onion varieties. Their mild flavor profile means you can enjoy them raw, but they’re equally delicious cooked.
These onions are a good source of vitamin C, B6, and folate, potassium and manganese as well as quercetin, an antioxidant known for its anti-inflammatory properties, and fiber. They’re available from April to August; look for their trademark logo as well as their flatter shape.
Quick Kitchen Nugget
Storing Onions
Vidalias have a high moisture content, and some experts recommend wrapping each one in a paper towel and storing them in the crisper drawer of your fridge. If you’re going to be using them in a few days, you can keep them on a rack in a cool, dry cabinet. But always keep any onions far away from potatoes because the ethylene gas produced by onions will cause your spuds to spoil prematurely.
For Your Best Health
Are You Getting Enough B12?
Vitamin B12 is essential for helping your body make DNA, red blood cells, and healthy nerve tissue. While there are guidelines for daily intake, that amount may not actually be enough to protect the brain in later years. Researchers at the University of California San Francisco (UCSF) found that older adults with “normal” but lower levels of active B12 showed signs of slower thinking, delayed visual processing, and more damage to the brain’s white matter — the communication highways that help different brain regions work together. The findings raise the possibility that some people may be told their B12 status is fine while their brains are already showing early signs of strain.
For the study, published in Annals of Neurology, researchers enrolled 231 healthy older adults through the Brain Aging Network for Cognitive Health (BrANCH) study at UCSF. The participants had an average age of 71, and none had dementia or mild cognitive impairment. Their average blood B12 level was 414.8 pmol/L, far above the US minimum cutoff of 148 pmol/L. Instead of relying only on total B12, the researchers focused on the biologically active form of the vitamin, which may better reflect how much B12 the body can actually use. The study focused on older adults, a group that may be especially sensitive to lower B12 because absorption can become less efficient with age. Some medications, digestive conditions, and diets low in animal-based foods can also increase the risk of low B12.
After adjusting for age, sex, education, and cardiovascular risk factors, the team found that participants with lower active B12 had slower processing speed on cognitive tests. The effect was stronger with older age. They also had delayed responses to visual stimuli, pointing to slower visual processing and reduced brain signaling efficiency.
MRI scans added another warning sign. Participants with lower active B12 had a higher volume of white matter lesions, which are areas of brain injury that have been linked to cognitive decline, dementia, and stroke risk. Even in this relatively healthy group, lower levels of active B12 were linked to slower thinking, slower visual processing, and more visible injury in the brain’s white matter.
The work was led by senior author Ari J. Green, MD, of the UCSF Departments of Neurology and Ophthalmology and the Weill Institute for Neurosciences. Dr. Green and his colleagues said the results call attention to a possible weakness in current B12 guidelines. The minimum threshold used to define deficiency may not capture early functional changes in the nervous system.
“Previous studies that defined healthy amounts of B12 may have missed subtle functional manifestations of high or low levels that can affect people without causing overt symptoms,” said Dr. Green, noting that clear deficiencies of the vitamin are commonly associated with a type of anemia. “Revisiting the definition of B12 deficiency to incorporate functional biomarkers could lead to earlier intervention and prevention of cognitive decline.”
The findings suggest that low but technically normal B12 could have broader effects than previously recognized. These levels could “impact cognition to a greater extent than what we previously thought and may affect a much larger proportion of the population than we realize,” said co-first author Alexandra Beaudry-Richard, MSc, who is currently completing her doctorate in research and medicine at the UCSF Department of Neurology and the Department of Microbiology and Immunology at the University of Ottawa.
“In addition to redefining B12 deficiency, clinicians should consider supplementation in older patients with neurological symptoms even if their levels are within normal limits,” she said. “Ultimately, we need to invest in more research about the underlying biology of B12 insufficiency, since it may be a preventable cause of cognitive decline.”
The UCSF findings do not prove that lower active B12 directly causes cognitive decline, and they do not mean every older adult should begin taking supplements without medical guidance. They do, however, suggest that the current definition of B12 deficiency may be too blunt for brain health.
Fitness Flash
The Benefits of 30 Minutes of Weekly Exercise
Current health recommendations suggest exercising for at least 2.5 hours each week, with 5 hours considered even better. For many people, that target can seem overwhelming. Here’s music to their ears: According to researchers at the Norwegian University of Science and Technology (NTNU), you may not need hours at the gym to boost your health after all. Studies from the past two decades suggest that just 30 minutes of high-intensity exercise per week can improve health. That works out to roughly 4.3 minutes per day or about 10 minutes every other day.
The important part is intensity. The activity needs to be strenuous enough to leave you noticeably out of breath. If you use a heart rate monitor, researchers say your heart rate should reach about 85 percent of your maximum. However, special equipment is not necessary. A simple way to judge intensity is by how difficult it is to talk. You should still be able to speak in short sentences, but you should not be able to sing or carry on a continuous conversation comfortably.
“The biggest reported challenge regarding exercise is lack of time. But with intense, short workouts, this is no longer a valid excuse,” said Ulrik Wisløff, a professor at NTNU and head of CERG, a research group that studies the health effects of exercise. Researchers say even a small amount of high-intensity activity can improve cardiovascular fitness, which plays a major role in long-term health. “Cardiovascular fitness is the best indicator of current and future health. Good cardio fitness reduces the risk of over 30 lifestyle diseases as well as premature death by 40 to 50 percent,” explained Wisløff.
CERG first documented these effects in a 2006 study that analyzed health information from 60,000 people. Since then, additional large studies from Norway and other countries have reported similar findings.
Rather than doing one intense 30-minute workout each week, it’s best to spread out the sessions, said Wisløff. Blood pressure and blood sugar control improve for 24 to 48 hours after a workout that pushes you hard enough to become breathless for several minutes. Because of these short-term benefits, divide exercise across two to four days per week whenever possible.
That does not necessarily mean sprinting at full speed or using the highest resistance setting on an exercise bike. “Your own personal fitness level determines what gives you a high heart rate,” Wisløff said. “If you are not very fit, simply taking a brisk walk may be enough. Having said that, you need to walk fast enough that you get quite out of breath. You can then increase the intensity as your fitness improves. Short intervals are effective. For example, this could be bursts of 45 seconds with 15-second breaks. Or like in Tabata workouts, with intense 20-second intervals interspersed with 10-second breaks. Otherwise, 4×4 intervals are recognized as highly effective for increasing oxygen uptake.”
“Fitness is something you have to maintain. Cardio fitness and strength decline quickly when not maintained, especially as you get older,” said Atefe R. Tari, PhD, a researcher and head of CERG’s initiative on exercise and brain health. Strength training is also considered important, particularly for middle-aged and older adults. “We know that strength training is important, especially for middle-aged and older adults. There is limited research on how strength training affects lifespan, but a HUNT study exploring this is due to be published soon,” said Wisløff. “Physical health and brain health are closely linked, and cardio fitness is key here as well. Exercise leads to the formation of new brain cells,” added Dr. Tari.
Wisløff and Tari are now encouraging Norwegian health authorities to revise the country’s official exercise recommendations, arguing that exercise intensity should receive greater emphasis.
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