Black-and-White Cookies Recipe, Spotlight on Vanilla Pods, Rotating Cookie Sheets, Coffee and Brain Health and A Surprising Way to Make Exercise Work Better
Vanilla or chocolate? You don’t have to decide when you indulge in a classic black-and-white cookie, the treat that’s more cake than biscuit with two luscious glazes. I’m also sharing two interesting food-related studies. According to the first, drinking coffee or tea could protect brain health. And according to the second, the keto diet could boost the effects of exercise for some people with high blood sugar.
Black-and-White Cookies

Healthy Ingredient Spotlight
Vanilla Pods

One of the most tantalizing tastes in the world, vanilla comes from pods that grow on a specific orchid, Vanilla planifolia—the only orchid grown commercially for its fruit. Producing the coveted pods is labor-intensive. Following hand pollination, it takes nine months for the pods to ripen and another three months to cure. (The process to create vanilla extract and vanilla paste takes even more time.)
Within each vanilla pod are thousands of seeds that add rich flavor and visual appeal to baked goods, custards, and ice cream. To get at the seeds, use the tip of a sharp paring knife to score the length of the pod, then one side of the blade to scrape them out. Add the leftover pod to a jar of sugar to make your own vanilla sugar for other recipes.

Quick Kitchen Nugget
Rotating Cookie Sheets
When baking cookies, rotating the sheet pan or cookie sheets halfway through the bake time is better for even rising and browning. This is true even when baking one sheet at a time. If a recipe suggests baking two sheets at one time, you want to not only rotate each one, but also switch their positions in the oven.

For Your Best Health
Coffee and Brain Health

Couples who intentionally pause to appreciate the enjoyable experiences they share tend to be more satisfied in their relationships, argue less, and feel more confident that their partnership will endure, according to researchers at the University oYour morning coffee or tea could be quietly supporting your brain health. A large prospective cohort study conducted by researchers from Mass General Brigham, Harvard T.H. Chan School of Public Health, and the Broad Institute of MIT and Harvard examined data from 131,821 participants in the Nurses' Health Study (NHS) and Health Professionals Follow-Up Study (HPFS). It found that moderate consumption of caffeinated coffee or tea was linked to an 18% lower risk of dementia, slower cognitive decline, and better preservation of cognitive abilities. The benefits appeared strongest at 2 to 3 cups of coffee or 1 to 2 cups of tea daily—and even held true for people genetically predisposed to dementia. The study was published in JAMA.
"When searching for possible dementia prevention tools, we thought something as prevalent as coffee may be a promising dietary intervention—and our unique access to high quality data through studies that have been going on for more than 40 years allowed us to follow through on that idea," said senior author Daniel Wang, MD, ScD, associate scientist with the Channing Division of Network Medicine in the Mass General Brigham Department of Medicine, and assistant professor at Harvard Medical School and in the Department of Nutrition at Harvard Chan School. "While our results are encouraging, it's important to remember that the effect size is small and there are lots of important ways to protect cognitive function as we age. Our study suggests that caffeinated coffee or tea consumption can be one piece of that puzzle."
Preventing dementia early is especially important because current treatments are limited and generally provide only modest benefits after symptoms begin. As a result, scientists are increasingly focusing on lifestyle factors, including diet, that may influence the development of cognitive decline.
Coffee and tea contain compounds such as polyphenols and caffeine, which are thought to support brain health. These substances may help reduce inflammation and limit cellular damage, both of which are linked to cognitive decline. Previous research on coffee and dementia has produced mixed results, often due to shorter study periods or limited data on long-term consumption patterns and different types of beverages.
"We also compared people with different genetic predispositions to developing dementia and saw the same results, meaning coffee or caffeine is likely equally beneficial for people with high and low genetic risk of developing dementia," said lead author Yu Zhang, MBBS, MS, a PhD student at Harvard Chan School and a research trainee at Mass General Brigham.f Illinois Urbana-Champaign. Soaking in their happy moments together—whether reminiscing about a favorite memory, enjoying a dinner together, or looking forward to something exciting—may be building a powerful shield for their relationship.

Fitness Flash
A Surprising Way to Make Exercise Work Better
Advice about staying healthy often centers on regular exercise and limiting fatty foods. Physical activity helps people shed excess weight, build muscle, and strengthen the heart. It also improves the body's ability to absorb and use oxygen to produce energy, which is considered one of the most reliable indicators of long-term health and longevity.
However, people with high blood sugar frequently miss out on some of these benefits from exercise, particularly improvements in how efficiently their bodies use oxygen. Elevated blood sugar raises the risk of heart and kidney disease. It can also interfere with the ability of muscles to increase oxygen uptake during physical activity. For people facing this challenge, new research suggests an unexpected possibility. Instead of reducing fat intake, increasing it might help.
A study led by Sarah Lessard, PhD, associate professor at the Fralin Biomedical Research Institute at VTC Center for Exercise Medicine Research and exercise medicine researcher, and published in Nature Communications examined how diet affects exercise response. The team found that mice fed a high-fat ketogenic diet experienced a drop in high blood sugar, also known as hyperglycemia. Their bodies also became more responsive to exercise.
"After one week on the ketogenic diet, their blood sugar was completely normal, as though they didn't have diabetes at all," said Dr. Lessard. "Over time, the diet caused remodeling of the mice's muscles, making them more oxidative and making them react better to aerobic exercise."
The ketogenic diet gets its name from ketosis, a metabolic state in which the body switches from using sugar as its main fuel to burning fat. Because the diet relies on high-fat foods and severely limits carbohydrates, it contrasts with the low-fat diets traditionally recommended by many health experts.
The keto diet has been associated with health benefits for certain conditions, including epilepsy and Parkinson's disease. Historically, it was also used to manage diabetes. Before insulin was discovered in the 1920s, doctors sometimes relied on this approach to help lower blood sugar.
Dr. Lessard's earlier studies showed that people with elevated blood sugar often have reduced exercise capacity. This led her to explore whether a ketogenic diet could help restore the body's ability to adapt to exercise. In the study, mice ate a high-fat, low-carbohydrate diet and ran regularly on exercise wheels. Over time, their muscles developed more slow-twitch fibers, which are linked to greater endurance. "Their bodies were more efficiently using oxygen, which is a sign of higher aerobic capacity," Dr. Lessard said.
According to Dr. Lessard, exercise benefits nearly every tissue in the body, including fat tissue. But growing evidence suggests that the greatest improvements in health occur when diet and exercise are combined rather than treated as separate strategies.
"What we're really finding from this study and from our other studies is that diet and exercise aren't simply working in isolation," said Dr. Lessard. "There are a lot of combined effects, and so we can get the most benefits from exercise if we eat a healthy diet at the same time."
She plans to expand the research to human participants to determine whether people experience the same improvements seen in mice. She also points out that following a ketogenic diet can be difficult. For many people, a less restrictive eating plan such as the Mediterranean diet may be easier to maintain while still supporting healthy blood sugar levels. This approach includes carbohydrates from whole foods like fruits, vegetables, and whole grains instead of eliminating carbohydrates entirely. "Our previous studies have shown that any strategy you and your doctor have arrived at to reduce your blood sugar could work," she said.
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